PMID: 9553787Apr 29, 1998Paper

Correspondence between occupational exposure limit and biological action level values for alkoxyethanols and their acetates

International Archives of Occupational and Environmental Health
J Laitinen

Abstract

The Finnish occupational exposure limit (OEL) values for alkoxyethanols and their acetates were lowered in 1996. A reevaluation of the correspondence between the new OEL value and the biological action level (BAL) was thus needed. This study was conducted in silkscreen printing enterprises, where 2-alkoxyethanols and their acetates are mainly used as solvents. The air/urine correlations between 2-methoxyethylacetate, 2-ethoxyethylacetate, 2-butoxyethanol, 2-butoxyethylacetate, and 2-methoxyacetic (MAA), 2-ethoxyacetic (EAA), and 2-butoxyacetic acid (BAA) were evaluated on an individual and time-related basis at four different enterprises. Inhalation exposure to alkoxyalcohols and their acetates was monitored with diffusion badges (n = 38) for an entire work week. Urinary excretion of alkoxyacetic acids immediatley after the shift and at 14-16 h after exposure (n = 112) was analyzed by a gas chromatograph equipped with a flame-ionization detector. Inhalation exposure to 2-methoxyethylacetate at 0.5 cm3/m3 corresponded to MAA excretion of 3 mmol/mol creatinine in urine at 14 to 16 hours after exposure. The next-morning urinary EAA excretion of 37 mmol/mol creatinine corresponded to an 8-h 2-ethoxyethylacetate exposure of 2 cm3/m3...Continue Reading

Citations

Feb 3, 2005·International Archives of Occupational and Environmental Health·S KezicI Jakasa
Jun 7, 2002·Applied Occupational and Environmental Hygiene·Brit E Todd, Roy M Buchan
Dec 20, 2005·Journal of Occupational and Environmental Hygiene·Joseph O'NeilJyl Madlem
Jun 14, 2000·Critical Reviews in Toxicology·G Johanson
Nov 7, 2003·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·K Jones, J Cocker
Oct 23, 2008·Chemico-biological Interactions·Aaron GrossLakshmaiah Sreerama
Aug 8, 2008·Human & Experimental Toxicology·P J Boogaard
Jul 24, 1998·Journal of Occupational and Environmental Medicine·J LaitinenH Savolainen
Mar 24, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Andrea LovatoGino Marioni
Nov 8, 2014·Annals of Occupational and Environmental Medicine·Ji-Hye KimSang-Gil Lee
Nov 9, 2010·Journal of Occupational and Environmental Hygiene·Farhang Akbar-KhanzadehMahboubeh Akbar-Khanzadeh
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Nov 24, 2011·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Ki-Hyun KimJong-Tae Lee
Apr 22, 2018·Environmental Science and Pollution Research International·Farzad Davardoost, Davood Kahforoushan

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