Cortical local and long-range synchronization interplay in human absence seizure initiation

NeuroImage
Frédérique AmorMichel Le Van Quyen

Abstract

Brain activity relies on transient, fluctuating interactions between segregated neuronal populations. Synchronization within a single and between distributed neuronal clusters reflects the dynamics of these cooperative patterns. Thus absence epilepsy can be used as a model for integrated, large-scale investigation of the emergence of pathological collective dynamics in the brain. Indeed, spike-wave discharges (SWD) of an absence seizure are thought to reflect abnormal cortical hypersynchronization. In this paper, we address two questions: how and where do SWD arise in the human brain? Therefore, we explored the spatio-temporal dynamics of interactions within and between widely distributed cortical sites using magneto-encephalographic recordings of spontaneous absence seizures. We then extracted, from their time-frequency analysis, local synchronization of cortical sources and long-range synchronization linking distant sites. Our analyses revealed a reproducible sequence of 1) long-range desynchronization, 2) increased local synchronization and 3) increased long-range synchronization. Although both local and long-range synchronization displayed different spatio-temporal profiles, their cortical projection within an initiation ti...Continue Reading

References

Sep 1, 1990·Electroencephalography and Clinical Neurophysiology·T InouyeS Ukai
Jan 1, 1984·Cleveland Clinic Quarterly·H LüdersH H Morris
Feb 1, 1997·NeuroImage·K J Friston
Jan 5, 2000·Human Brain Mapping·J P LachauxF J Varela
Mar 4, 2000·Proceedings of the National Academy of Sciences of the United States of America·N KopellR D Traub
Dec 5, 2000·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·A von Stein, J Sarnthein
Feb 13, 2001·Journal of Physiology, Paris·W J Freeman
Apr 17, 2001·The Behavioral and Brain Sciences·P L Nunez
Jan 24, 2002·Proceedings of the National Academy of Sciences of the United States of America·Antoine LutzFrancisco J Varela
May 4, 2002·Nature Reviews. Neuroscience·Vincenzo Crunelli, Nathalie Leresche
May 15, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·P A RobinsonD L Rowe
Apr 16, 2003·Epilepsy Research·Florian MormannChristian E Elger
May 29, 2003·IEEE Transactions on Bio-medical Engineering·Mario ChávezJacques Martinerie
Nov 10, 2004·Proceedings of the National Academy of Sciences of the United States of America·Antoine LutzRichard J Davidson
Feb 22, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Michel Le Van QuyenJacques Martinerie
Apr 15, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·J Matias PalvaKai Kaila
Aug 24, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C J Stam
Sep 2, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Luis Garcia DominguezJose Luis Perez Velazquez
May 27, 2006·Neuroscience and Biobehavioral Reviews·Gilles van Luijtelaar, Evgenia Sitnikova
Aug 4, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Peter J UhlhaasEugenio Rodriguez
Jan 17, 2007·NeuroImage·C A SchevonF Gilliam
Jun 15, 2007·Trends in Neurosciences·Michel Le Van Quyen, Anatol Bragin
Jun 15, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Pierre-Olivier PolackStéphane Charpier

❮ Previous
Next ❯

Citations

Jun 5, 2013·Cognitive Neurodynamics·Moira L Steyn-RossJamie W Sleigh
Aug 24, 2010·Epilepsia·Friederike MoellerJean Gotman
May 18, 2011·Computational Intelligence and Neuroscience·François TadelRichard M Leahy
Apr 30, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xiaoxiao BaiHal Blumenfeld
Mar 13, 2014·Proceedings of the National Academy of Sciences of the United States of America·Zachary V FreudenburgEric C Leuthardt
May 3, 2011·Medical & Biological Engineering & Computing·Disha GuptaGilles van Luijtelaar
Nov 26, 2010·Expert Review of Neurotherapeutics·Dimitrios I TsiptsiosMichail A Koutroumanidis
Dec 9, 2015·Journal of Neuroscience Methods·Khalid HamandiKrish D Singh
Oct 7, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Fabio RotondiFerruccio Panzica
Jul 6, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Dong WenXiaoli Li
Nov 26, 2010·Neurophysiologie clinique = Clinical neurophysiology·F WalloisR Grebe
Dec 19, 2015·Epilepsy Research·Yvonne J W RozendaalPauly P W Ossenblok
Jul 22, 2014·Annals of Neurology·Jeffrey R TenneyDouglas F Rose
Jun 15, 2013·Epilepsy Research·Jeffrey R TenneyDouglas F Rose
Dec 30, 2014·Current Opinion in Neurobiology·Sina Fazelpour, Evan Thompson
May 26, 2009·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J L Perez VelazquezL Garcia Dominguez
Jun 2, 2009·Journal of Neuroscience Methods·Klaus LehnertzTobias Wagner
Dec 29, 2013·Seizure : the Journal of the British Epilepsy Association·Palma PirosBela Clemens
Nov 6, 2012·Experimental Neurology·Annika LüttjohannGilles van Luijtelaar
Feb 24, 2015·Frontiers in Physiology·Annika Lüttjohann, Gilles van Luijtelaar
Sep 17, 2014·Frontiers in Neurology·Patrick W Carney, Graeme D Jackson
Feb 18, 2014·Journal of Child Neurology·Eliza Jacobs-BrichfordJeffrey R Tenney
Jan 20, 2018·Physical Review. E·D M MateosJ L Perez Velazquez
Jan 20, 2018·Physical Review. E·Vladimir A MaksimenkoStefano Boccaletti
Oct 9, 2020·Journal of Clinical Neurology·Eun Hee KimMi Sun Yum
Nov 10, 2020·International Journal of Neural Systems·Sisi JiangCheng Luo
Feb 8, 2018·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ptolemaios G SarrigiannisRichard Grünewald
Jul 27, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ami KumarNatia Japaridze

❮ Previous
Next ❯

Related Concepts

Related Feeds

Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.