Cortical morphologic features of axillary lymph nodes as a predictor of metastasis in breast cancer: in vitro sonographic study.

AJR. American Journal of Roentgenology
Deepak G BediKelly K Hunt

Abstract

The purpose of this study was in vitro sonographic-pathologic correlation of findings in dissected axillary lymph nodes from breast cancer patients undergoing axillary lymph node dissection and classification of the sonographic appearance of the nodes on the basis of cortical morphologic features to facilitate early recognition of metastatic disease. High-resolution sonography was used for in vitro examination of 171 lymph nodes from 19 axillae in 18 patients with unknown nodal status who underwent axillary lymph node dissection for early infiltrating breast cancer. The images were evaluated by two blinded observers, and discordant readings were referred to a third blinded observer. Each lymph node was classified as one of types 1-6 according to cortical morphologic features. Types 1-4 were considered benign, ranging from hyperechoic with no visible cortex to thickened generalized hypoechoic cortical lobulation. Type 5 (focal hypoechoic cortical lobulation) and type 6 (hypoechoic node with absent hilum) nodes were considered metastatic. The reference standard for metastatic disease was histopathologic evaluation of sectioned nodes by a single pathologist blinded to sonographic findings. Largest nodal diameter also was measured....Continue Reading

References

Dec 1, 1990·AJR. American Journal of Roentgenology·L RubaltelliP Cagol
Mar 1, 1989·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·M PamiloE M Lavast
Apr 1, 1996·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J S VaidyaI Mittra
Mar 1, 1996·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·W T YangC Metreweli
May 18, 1999·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·T TateishiK Shirouzu
Apr 25, 2006·AJR. American Journal of Roentgenology·Soledad AlvarezJulia Cortés

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Citations

Aug 11, 2010·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Ichiro OginoTakashi Ishikawa
Jun 30, 2010·Annals of Surgical Oncology·M Catherine LeeChristine Laronga
Dec 24, 2010·AJR. American Journal of Roentgenology·Leopoldo RubaltelliRoberto Stramare
Feb 26, 2014·Annals of Surgical Oncology·Roberto E KusminskyJames P Boland
Oct 24, 2014·AJR. American Journal of Roentgenology·Deanna L LaneWei Tse Yang
Mar 13, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sandy C LeeMary W Yamashita
Nov 11, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jose M NetMonica M Yepes
Nov 11, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Kathryn L HumphreyElizabeth A Rafferty
Aug 24, 2013·Radiology·Regina J HooleyLiane E Philpotts
Oct 11, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jacob S EcanowJan M Jeske
Jun 19, 2013·Seminars in Ultrasound, CT, and MR·Rosalind P CandelariaGary J Whitman
May 15, 2013·The Journal of Surgical Research·Leisha C ElmoreJulie A Margenthaler
Oct 16, 2012·Clinical Breast Cancer·Jennifer E JohM Catherine Lee
Aug 11, 2012·Current Problems in Cancer·Christina J Wai
Jul 25, 2013·Insights Into Imaging·Surekha JoshiPriscilla J Slanetz
Jul 26, 2011·Seminars in Ultrasound, CT, and MR·Wei Tse Yang
Sep 25, 2015·The Breast Journal·Zahraa Al-HilliJudy C Boughey
Dec 1, 2015·Seminars in Radiation Oncology·Ana P Lourenco, Martha B Mainiero
Sep 16, 2015·Diagnostic and Interventional Imaging·F MaxwellC de Bazelaire
Oct 20, 2012·Journal of Experimental & Clinical Cancer Research : CR·Francesco M SolivettiAldo Di Carlo
Sep 24, 2015·AJR. American Journal of Roentgenology·Basak Erguvan DoganWei Tse Yang
Aug 19, 2015·International Journal of Radiation Oncology, Biology, Physics·Simona F ShaitelmanGary J Whitman
Apr 22, 2015·The Journal of Surgical Research·Iheoma Y NwaoguJulie A Margenthaler
Dec 24, 2014·Insights Into Imaging·V DialaniP J Slanetz
Jan 28, 2015·Radiology·Romuald FerréBenoît Mesurolle
Jun 25, 2016·Current Problems in Diagnostic Radiology·Sean D RajGary J Whitman
Oct 12, 2016·AJR. American Journal of Roentgenology·Kyungmin ShinWei Yang
Jun 28, 2011·AJR. American Journal of Roentgenology·Deepak G Bedi

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