Cortical plasticity: from synapses to maps

Annual Review of Neuroscience
D V Buonomano, M M Merzenich

Abstract

It has been clear for almost two decades that cortical representations in adult animals are not fixed entities, but rather, are dynamic and are continuously modified by experience. The cortex can preferentially allocate area to represent the particular peripheral input sources that are proportionally most used. Alterations in cortical representations appear to underlie learning tasks dependent on the use of the behaviorally important peripheral inputs that they represent. The rules governing this cortical representational plasticity following manipulations of inputs, including learning, are increasingly well understood. In parallel with developments in the field of cortical map plasticity, studies of synaptic plasticity have characterized specific elementary forms of plasticity, including associative long-term potentiation and long-term depression of excitatory postsynaptic potentials. Investigators have made many important strides toward understanding the molecular underpinnings of these fundamental plasticity processes and toward defining the learning rules that govern their induction. The fields of cortical synaptic plasticity and cortical map plasticity have been implicitly linked by the hypothesis that synaptic plasticity ...Continue Reading

References

Feb 1, 1978·The Journal of Comparative Neurology·D H HubelM P Stryker
Oct 19, 1979·Brain Research·W B Levy, O Steward
May 1, 1978·Journal of Neurophysiology·D J Simons
Aug 20, 1976·Brain Research·S LeVay, C D Gilbert
Aug 1, 1992·Progress in Neurobiology·T Tsumoto
May 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·S M Dudek, M F Bear
Feb 1, 1992·Electroencephalography and Clinical Neurophysiology·P FuhrM Hallett
Oct 1, 1992·Journal of Neurophysiology·M Armstrong-JamesA Das-Gupta
Mar 12, 1992·Nature·C D Gilbert, T N Wiesel
Jul 1, 1992·Neuron·C D Gilbert
Nov 1, 1991·Journal of Neurophysiology·E E ClothiauxL N Cooper
Jan 1, 1991·Annual Review of Neuroscience·D V MadisonR A Nicoll
Jan 1, 1991·Annual Review of Neuroscience·J H Kaas
Jan 1, 1990·Cold Spring Harbor Symposia on Quantitative Biology·M M MerzenichK A Grajski
Jan 1, 1990·Annual Review of Neuroscience·T H BrownC L Keenan
Apr 22, 1990·The Journal of Comparative Neurology·P E Garraghty, M Sur

❮ Previous
Next ❯

Citations

Feb 13, 2001·Journal of Neuroscience Research·S Peña De Ortiz, Y Arshavsky
Nov 8, 2005·Indian Journal of Pediatrics·Nandini Mundkur
May 5, 2006·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·C Voelcker-RehageU M Staudinger
Jan 10, 2008·Experimental Brain Research·Veijo VirsuPekka Lahti-Nuuttila
Nov 6, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Tung-Hsin WuJason J S Lee
Dec 8, 2004·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jeffrey G OjemannHarold Burton
Jan 30, 2007·Journal of Neurology·S SchneiderT F Münte
Feb 24, 2006·Biological cybernetics·Peter König, Norbert Krüger
Apr 6, 2013·Biological cybernetics·Christian R Huyck, Peter J Passmore
Jun 21, 2007·Journal of Neural Transmission·Th Mulder
Mar 10, 2007·Journal of the Association for Research in Otolaryngology : JARO·Lina A J ReissBruce J Gantz
Mar 30, 2011·Brain Topography·Laurel J TrainorDaniel J Bosnyak
Feb 28, 2006·Journal of Computational Neuroscience·E BartD Holcman
May 25, 2005·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Neal Prakash, Ron D Frostig
Feb 2, 2013·Cognitive Neurodynamics·Yoshinori IdeTakeshi Aihara
Jun 29, 2004·Behavioural Brain Research·Stéphanie BourgeonJacques-Olivier Coq
Mar 17, 2004·Current Opinion in Neurobiology·Elisabeth Foeller, Daniel E Feldman
Mar 17, 2004·Current Opinion in Neurobiology·Karl Kandler
Apr 9, 2013·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Jill M ZemianekThomas B Shea
May 26, 2005·Neuroscience Letters·Yew Long LoS Fook-Chong
Nov 19, 2003·Neural Networks : the Official Journal of the International Neural Network Society·Karl Friston
Oct 3, 2006·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Jaime Grutzendler, Wen-Biao Gan
May 12, 2005·Progress in Neurobiology·James H Cauraugh, Jeffery J Summers
Nov 20, 2003·Trends in Neurosciences·Hollis Cline
Feb 11, 2004·Experimental Neurology·Donna L MaierJames S McCasland
Feb 11, 2004·Experimental Neurology·Reha S Erzurumlu
Sep 23, 2000·Journal of Communication Disorders·D R Irvine

❮ Previous
Next ❯

Methods Mentioned

BETA
amputation

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.