Cortical reorganization in recent-onset tinnitus patients by the Heidelberg Model of Music Therapy

Frontiers in Neuroscience
Christoph M KrickHans Volker Bolay

Abstract

Pathophysiology and treatment of tinnitus still are fields of intensive research. The neuroscientifically motivated Heidelberg Model of Music Therapy, previously developed by the German Center for Music Therapy Research, Heidelberg, Germany, was applied to explore its effects on individual distress and on brain structures. This therapy is a compact and fast application of nine consecutive 50-min sessions of individualized therapy implemented over 1 week. Clinical improvement and long-term effects over several years have previously been published. However, the underlying neural basis of the therapy's success has not yet been explored. In the current study, the therapy was applied to acute tinnitus patients (TG) and healthy active controls (AC). Non-treated patients were also included as passive controls (PTC). As predicted, the therapeutic intervention led to a significant decrease of tinnitus-related distress in TG compared to PTC. Before and after the study week, high-resolution MRT scans were obtained for each subject. Assessment by repeated measures design for several groups (Two-Way ANOVA) revealed structural gray matter (GM) increase in TG compared to PTC, comprising clusters in precuneus, medial superior frontal areas, an...Continue Reading

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Citations

Jul 25, 2017·Frontiers in Neuroscience·Christoph M KrickWolfgang Reith
Mar 13, 2020·Frontiers in Human Neuroscience·Shirui ChengFanrong Liang
May 31, 2020·Otolaryngologic Clinics of North America·Meredith E AdamsSteven W Cheung
Apr 11, 2021·Progress in Neuro-psychopharmacology & Biological Psychiatry·Han LvZhenchang Wang

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