DOI: 10.1101/487173Dec 4, 2018Paper

Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits

BioRxiv : the Preprint Server for Biology
Tobias KaufmannLars T. Westlye


Neurodevelopmental trajectories are shaped by interactions between coordinated biological processes and individual experiences throughout ontogeny, yet the specific genetic and environmental impact on brain development is enigmatic. Here, we map the genetic architectures of cognitive traits and psychiatric disorders onto the brain, show that such canonical genetic maps are associated with individual normative patterns in youths, and provide evidence that trauma exposure and parental education may alter this relationship.

Related Concepts

Mental Disorders
Chromosome Mapping
Genetic Activator
Brain Development
Neurodevelopmental Disorders

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