Cortico-spinal excitability and hand motor recovery in stroke: a longitudinal study

Journal of Neurology
Jitka VeldemaDennis A Nowak

Abstract

To describe the relationship between changes of cortico-spinal excitability and motor recovery of the affected hand after stroke. Eighteen hemiparetic stroke patients with a severe-to-mild upper limb motor impairment were randomized. Cortico-spinal excitability measures (resting motor thresholds and motor evoked potentials) obtained from a distal (abductor pollicis brevis) and proximal (biceps brachii) upper limb muscle were assessed for both hemispheres. Motor function of the affected hand was tested by the Wolf Motor Function and Action Research Arm tests. The evaluations were performed at baseline and weekly over 7 weeks of in-patient neurological rehabilitation. Severe hand dysfunction was associated with a strong suppression of ipsilesional cortico-spinal excitability and a shift of excitability towards the contralesional hemisphere. Mild hand impairment was associated with a shift of cortico-spinal excitability towards the ipsilesional hemisphere. Favorable motor recovery correlated with an increase of ipsilesional cortico-spinal excitability.

References

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Citations

Dec 18, 2018·Frontiers in Neurology·Charlotte Rosso, Jean-Charles Lamy
May 1, 2019·Frontiers in Neurology·Yeun Jie YooSeong Hoon Lim
Apr 8, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marina Berenguer-RochaKátia Monte-Silva
May 8, 2021·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Victoria Fernández
Jun 29, 2021·Journal of Motor Behavior·Kiyoshige IshibashiYutaka Kohno
Nov 5, 2021·Journal of Neuroengineering and Rehabilitation·Jitka VeldemaAlireza Gharabaghi

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