Corticoid therapy for overlapping syndromes in an HIV-positive patient

Internal Medicine
Yu KakuMasahiro Yamamoto

Abstract

Human immunodeficiency virus (HIV) infection disturbs the host's immune function and often coexists with various autoimmune and/or systemic rheumatic diseases with manifestations that sometimes overlap with each other. We herein present the case of a 43-year-old Japanese man infected with HIV who exhibited elevated serum creatine kinase and transaminases levels without any symptoms. He was diagnosed with autoimmune hepatitis, polymyositis and Sjögren's syndrome and received combined antiretroviral therapy (cART); however, the laboratory abnormalities persisted. We successfully administered cART with the addition of oral prednisolone, and the patient's condition recovered without side effects related to the metabolic or immunosuppressive effects of these drugs.

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Citations

Aug 22, 2016·Rheumatology International·Justyna Roszkiewicz, Elzbieta Smolewska
Jan 26, 2017·Medicine·Emilie VirotPascal Seve
Oct 3, 2019·AIDS·Maria Martínez-RebollarMontserrat Laguno
Sep 29, 2019·World Journal of Gastroenterology : WJG·Roongruedee ChaiteerakijSombat Treeprasertsuk

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