Corticoreticular pathways in the cat. II. Discharge activity of neurons in area 4 during voluntary gait modifications

Journal of Neurophysiology
B Kably, Trevor Drew

Abstract

We propose that the descending command from area 4 that is responsible, in part, for the change in limb trajectory required to step over an obstacle in one's path also plays a role in triggering the anticipatory postural modifications that accompany this movement. To test this hypothesis, we recorded the discharge characteristics of identified classes of corticofugal neurons in area 4 of the cat. Neurons were identified either as: pryamidal tract neurons (PTNs) if their axon projected to the caudal pyramidal tract (PT) but not to the pontomedullary reticular formation (PMRF); as corticoreticular neurons (CRNs) if their axon projected to the PMRF but not to the PT; and as PTN/CRNs if their axon projected to both structures. Altogether, the discharge properties of 212 corticofugal neurons (109 PTNs, 66 PTN/CRNs, and 37 CRNs) within area 4 were recorded during voluntary gait modifications. Neurons in all three classes showed increases in their discharge frequency during locomotion and included groups that increased their discharge either during the swing phase of the modified step, during the subsequent stance phase, or in the stance phase of the cycle preceding the step over the obstacle. A slightly higher percentage of CRNs (39%...Continue Reading

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Citations

May 30, 2012·The Journal of Physiology·Demetris S SoteropoulosStuart N Baker
Jul 11, 1998·Journal of Neurophysiology·B Kably, T Drew
Sep 4, 2015·Journal of Neural Engineering·J RigosaS Micera
Feb 12, 2017·Experimental Brain Research·Derek M MillerAndrew A McCall
Dec 14, 2005·Experimental Brain Research·T BhattY-C Pai
Jun 29, 2004·Experimental Brain Research·John A Buford, Adam G Davidson
Aug 31, 2006·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Serge Rossignol
Jan 6, 2006·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Elzbieta Jankowska, Stephen A Edgley
Dec 6, 2019·Frontiers in Neurology·Sung Ho Jang, Sung Jun Lee
Aug 9, 2003·Journal of Neurophysiology·Benedicte Schepens, Trevor Drew
Jan 24, 2018·Journal of Neurophysiology·Demetris S Soteropoulos

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