Corticospinal tract change in the unaffected hemisphere at the early stage of intracerebral hemorrhage: a diffusion tensor tractography study

European Neurology
So Young KwakSung Ho Jang

Abstract

Contribution by the unaffected hemisphere is one of the motor recovery mechanisms following stroke. We attempted to investigate changes in the corticospinal tract (CST) in the unaffected hemisphere at the early stage in patients with intracerebral hemorrhage (ICH), using diffusion tensor tractography (DTT). Fifty-three consecutive hemiparetic patients and 40 age- and sex-matched control subjects were enrolled. DTT was performed using a 1.5-tesla system at the early stage of ICH (7-28 days after onset). We measured the fiber number, fractional anisotropy and apparent diffusion coefficient of CST tractography in the unaffected hemisphere, and assessed the motor function of the affected extremities. The fiber number of the CST in the unaffected hemisphere of the patient group was higher than that of the control group (p = 0.000). In contrast, the fractional anisotropy value was lower than that of the control group (p = 0.018). However, there were no significant differences in the apparent diffusion coefficient values between the 2 groups (p = 0.654). We demonstrated that the CST in the unaffected hemisphere was changed at the early stage in patients with ICH, using DTT.

Citations

Sep 2, 2010·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Sung Ho Jang
Apr 3, 2013·Neurosurgical Focus·Michael M McDowellE Sander Connolly
May 16, 2012·Brain Injury : [BI]·Sang Seok YeoSung Ho Jang
Apr 23, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Tetsuo KoyamaKazuhisa Domen
Jan 26, 2016·Neural Regeneration Research·Jae Woon KimSung Ho Jang
May 28, 2015·Experimental Neurology·Neeraj ChaudharyGuohua Xi
Nov 16, 2011·The International Journal of Neuroscience·Sang Seok YeoSung Ho Jang
Apr 9, 2013·Neuroscience Letters·Sung Ho JangMin Cheol Chang
Apr 22, 2014·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Chicheng MaShengnian Zhou
May 6, 2014·Frontiers in Human Neuroscience·Hyeok Gyu KwonSung Ho Jang
Feb 28, 2013·Stroke; a Journal of Cerebral Circulation·Sung Ho JangSang Seok Yeo
Sep 22, 2020·Translational Stroke Research·Bastian VolbersArnd Doerfler
Jan 14, 2017·Frontiers in Human Neuroscience·Sahil BajajAndrew J Butler

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