Corticospinal tract changes in acute brainstem ischemic stroke patients: A diffusion kurtosis imaging study

Neurology India
Huiyou ChenXindao Yin

Abstract

The present study aimed to investigate the corticospinal tract (CST) changes in patients with brainstem ischemic stroke by using the diffusion kurtosis imaging (DKI) approach.. Twenty-one patients with brainstem stroke and 21 group-matched healthy controls underwent brain DKI with 3.0 T magnetic resonance imaging (MRI). The DKI was obtained by using three b values of 0, 1,000, 2,000 s/mm2 with 15 diffusion directions. Regions of interest (ROIs) were placed at four levels: the pons, posterior limb of the internal capsule (PLIC), corona radiata, and precentral gyrus. The DKI parameters, including fractional anisotropy (FA), mean diffusivity (MD), and mean kurtosis (MK) values, in these regions were measured from the contralateral to the ipsilateral side of patients and both the left and right sides of healthy controls at all the four selected levels. The ipsilateral side of the ischemic lesion showed a decrease in FA and MD and an increase in MK when compared with the contralateral normal region at all the four selected levels with statistically differences (P < 0.05). At these four selected levels, there were no differences between the left and right sides in healthy controls with MD, FA, and MK (P > 0.05). The MD values of the ...Continue Reading

References

Apr 17, 2008·Proteins·Ignacio Fdez GalvánMartin J Field
Jul 18, 2009·Lancet Neurology·Peter LanghorneAlex Pollock
Nov 28, 2017·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Jichen HeGaofeng Zeng

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Citations

Jul 25, 2020·Brain Imaging and Behavior·Mengye ShiLiping Wang

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