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Corticosteroid-Binding Globulin is expressed in the adrenal gland and its absence impairs corticosterone synthesis and secretion in a sex-dependent manner

Scientific Reports

Sep 30, 2019

Jose GulfoMar Grasa

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Abstract

Corticosteroid-binding globulin (CBG) is synthesized by the liver and secreted into the bloodstream where binds to glucocorticoids. Thus CBG has the role of glucocorticoid transport and free hormone control. In addition, CBG has been detected in some extrahepatic tissues without a known...read more

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Adrenal Cortex Hormones
Adrenal Gland Neoplasms
Adrenal Glands
Aldosterone
Corticosterone
Glucocorticoids
Hormones
Liver
Laboratory mice
Mitochondria
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Corticosteroid-Binding Globulin is expressed in the adrenal gland and its absence impairs corticosterone synthesis and secretion in a sex-dependent manner

Scientific Reports

Sep 30, 2019

Jose GulfoMar Grasa

PMID: 31570737

DOI: 10.1038/s41598-019-50355-1

Abstract

Corticosteroid-binding globulin (CBG) is synthesized by the liver and secreted into the bloodstream where binds to glucocorticoids. Thus CBG has the role of glucocorticoid transport and free hormone control. In addition, CBG has been detected in some extrahepatic tissues without a known...read more

Mentioned in this Paper

Adrenal Cortex Hormones
Adrenal Gland Neoplasms
Adrenal Glands
Aldosterone
Corticosterone

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