Corticosteroid-induced diabetes in palliative care

Journal of Palliative Medicine
Jana PilkeyXuan Li

Abstract

Corticosteroids are one of the most commonly used medications in palliative care. Although the benefit of corticosteroids generally outweighs the risk in the palliative population, side effects are common and necessitate careful consideration prior to prescribing. In March of 2010, a guideline for monitoring blood glucose values was implemented as part of our standard care within our two inpatient tertiary palliative care units. A retrospective study was conducted, the aim of which was twofold. First, we hoped to determine a prevalence rate for steroid-induced diabetes mellitus (SDM) in palliative care and whether or not screening glucose levels twice weekly was appropriate or required. Second, we wanted to determine if possible predictors existed for the development of SDM in a palliative population, thereby identifying the patients most at risk who would benefit from ongoing glucose monitoring. We found that SDM is more common in palliative care patients than previously thought. Our study showed a higher likelihood of developing hyperglycaemia with higher doses of dexamethasone. But although dose is correlated with hyperglycemia, patients without high doses were also at risk. Further study is currently underway with slight mo...Continue Reading

References

Jan 10, 1994·Archives of Internal Medicine·J H GurwitzJ Avorn
Feb 24, 2001·Palliative Medicine·J R HardyP Stone
Aug 11, 2001·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·S MercadanteA Casuccio
Sep 11, 2002·Journal of General Internal Medicine·David BlackburnMuhammad Mamdani
Mar 30, 2004·Palliative Medicine·Friedemann NauckUNKNOWN Working Group on the Core Documentation for Palliative Care Units in Germany
Jan 1, 2005·Current Opinion in Oncology·Evert C A Kaal, Charles J Vecht
Jun 15, 2005·European Journal of Cancer Care·R McCoubrieL Dawes
Jun 9, 2006·Acta Oncologica·Staffan H Lundström, Carl Johan Fürst
Aug 31, 2006·Journal of Pain and Symptom Management·Karen QuinnTrisha Dunning
Nov 30, 2006·Diabetes Care·Martin C GullifordRadoslav Latinovic
Jul 13, 2007·Molecular and Cellular Endocrinology·Alexandros Vegiopoulos, Stephan Herzig
May 21, 2009·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·John N Clore, Linda Thurby-Hay
Feb 3, 2011·Journal of Korean Medical Science·Seo Yun KimJae-Joon Yim

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Citations

Feb 11, 2016·Acta Diabetologica·Marco GalloGennaro Clemente
Feb 26, 2016·British Journal of Cancer·Custodia García-JiménezAntonio De la Vieja
Dec 17, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Ka-Eun YooByung Koo Lee
Mar 1, 2015·Cancer Treatment Reviews·G AriaansM Jalving
Oct 31, 2014·Oncology Nursing Forum·Veronica J BradyGeri LoBiondo-Wood
Jan 15, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hiromichi YamaneNagio Takigawa
Jan 15, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michael FrancoArun Azad
Apr 17, 2013·The American Journal of Hospice & Palliative Care·Naoki Matsuo, Kinomi Yomiya
Jan 26, 2016·International Journal of Palliative Nursing·Sarah BegleyMargaret O'Connor
Apr 20, 2019·Diabetic Medicine : a Journal of the British Diabetic Association·C K BoughtonR Hovorka
Sep 15, 2020·Modern Rheumatology·Hiroyuki NakamuraTatsuya Atsumi
Aug 29, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Gunnhild JakobsenØrnulf Paulsen
Sep 1, 2018·The American Journal of Hospice & Palliative Care·Leanna R JawardMichael A Smith
Sep 27, 2014·Current Opinion in Supportive and Palliative Care·Magnus LindskogCarl Johan Fürst
Jan 25, 2021·Experimental Eye Research·Ruchi ShahAlexander V Ljubimov
Mar 14, 2018·Diabetes Research and Clinical Practice·Aldo Bonaventura, Fabrizio Montecucco
Jul 10, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Nalinie Joharatnam-HoganUNKNOWN Joint British Diabetes Society for Inpatient Care (JBDS), UK Chemotherapy Board (UKCB)
Oct 16, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Younes R YounesBenjamin C T Field

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