Corticosteroids reduce postoperative morbidity after third molar surgery: a systematic review and meta-analysis

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Michael R MarkiewiczThomas B Dodson

Abstract

The purpose of this study was to apply meta-analytical methods to measure the effect of corticosteroids (CS) on edema, trismus, and pain at early and late postoperative periods after third molar (M3) removal. A systematic search of the literature was carried out to identify eligible articles. The primary predictor variable was perioperative CS exposure (yes or no). The 3 outcome variables were edema, trismus, and pain assessed during the early (1-3 days) and late (>3 days) postoperative time periods. Standardized mean differences (SMD) for edema and weighted mean differences (WMD) for trismus and pain were pooled across studies. Differences between the 2 treatment groups were assessed using random effects models and metaregressions for both early and late postoperative assessments. Twelve trials met the inclusion criteria. Subjects receiving CS had significantly less edema during both early (SMD, 1.4; 95% confidence interval [CI], 0.6, 2.2; P < .001) and late (SMD, 1.1; 95% CI, 0.1, 2.0; P = .03) time periods after surgery and less trismus than controls during the early and late postoperative periods (early WMD, 4.1 mm; 95% CI, 2.8 mm, 5.5 mm; P < .001; late WMD, 2.7 mm; 95% CI, 0.8 mm, 4.6 mm; P = .005). Average pain levels we...Continue Reading

References

Nov 1, 1975·Oral Surgery, Oral Medicine, and Oral Pathology·E J Messer, J J Keller
Nov 1, 1992·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·E A NeupertJ R Gordon
Jun 27, 1992·BMJ : British Medical Journal·R CollinsE Braunwald
Jun 1, 1991·Statistics in Medicine·T C Chalmers
May 1, 1991·Annals of Internal Medicine·J M PiperM R Griffin
Feb 1, 1990·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M T MontgomeryS W Redding
Feb 1, 1985·The British Journal of Oral & Maxillofacial Surgery·M ElHagM Harris
Feb 1, 1986·Oral Surgery, Oral Medicine, and Oral Pathology·O R Beirne, B Hollander
Apr 1, 1986·Taehan Ch'ikkwa Uisa Hyŏphoe Chi·S C LeeH J Kim
Sep 1, 1986·Controlled Clinical Trials·R DerSimonian, N Laird
Mar 1, 1987·Annals of Internal Medicine·C D Mulrow
Aug 1, 1985·Oral Surgery, Oral Medicine, and Oral Pathology·A L Sisk, G J Bonnington
Dec 1, 1984·International Journal of Oral Surgery·R A Seymour, J G Walton
May 1, 1983·Oral Surgery, Oral Medicine, and Oral Pathology·M M Amin, D M Laskin
Dec 1, 1983·The New England Journal of Medicine·T C ChalmersH Smith
Dec 1, 1982·International Journal of Oral Surgery·J van der ZwanL T van der Weele
Feb 1, 1995·JAMA : the Journal of the American Medical Association·K F SchulzD G Altman
Dec 1, 1994·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·T Hyrkäs
Nov 1, 1994·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·W P VallerandM Heft
Jun 1, 1993·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·T HyrkäsI Paakkari
Aug 28, 1996·JAMA : the Journal of the American Medical Association·C BeggD F Stroup
Aug 21, 1997·The New England Journal of Medicine·J LeLorierF Derderian
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Oct 31, 1998·BMJ : British Medical Journal·B Thornley, C Adams
Oct 12, 1999·JAMA : the Journal of the American Medical Association·R DerSimonian, R J Levine
Mar 7, 2000·Lancet·M Clarke
Oct 12, 2000·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·R E Alexander, R R Throndson
Feb 12, 2002·Statistics in Medicine·Hans C van HouwelingenTheo Stijnen
Jun 1, 2002·JAMA : the Journal of the American Medical Association·Carin M OlsonBrian Pace
May 8, 2003·The Journal of the American Dental Association·Anthony R Silvestri, Iqbal Singh
Aug 14, 2003·Fundamental & Clinical Pharmacology·Irismar Reis de OliveiraNalinee Poolsup
Feb 1, 1964·Oral Surgery, Oral Medicine, and Oral Pathology·L SZMYDA STUMPF
Jan 1, 1952·Oral Surgery, Oral Medicine, and Oral Pathology·T D SPIESA REBOREDO
May 27, 2004·JAMA : the Journal of the American Medical Association·An-Wen ChanDouglas G Altman
Jul 15, 2005·JAMA : the Journal of the American Medical Association·John P A Ioannidis
May 30, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Melike OrduluYusuf Emes
Aug 12, 2006·European Journal of Clinical Pharmacology·J M Micó-LlorensC Gay-Escoda
Nov 23, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M Cemil BuyukkurtOmer Kaya
Dec 13, 2006·International Journal of Oral and Maxillofacial Surgery·A Markovic, Lj Todorovic

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Citations

Jun 28, 2011·Evidence-based Dentistry·Thomas B Dodson
Nov 14, 2012·BMC Oral Health·Daniel Satnam Singh SaundThomas Dietrich
Dec 7, 2011·Medicina oral, patología oral y cirugía bucal·Manuel Sancho-PuchadesCosme Gay-Escoda
Aug 22, 2013·Clinical Oral Investigations·Oliver RistowChristoph Pautke
Jul 9, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Oliver RistowBettina Hohlweg-Majert
Dec 10, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Jennifer ChristensenAnn Wenzel
May 17, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Oliver RistowChristoph Pautke
Nov 21, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Stuart E LieblichMichael J Zak
Oct 2, 2012·Atlas of the Oral and Maxillofacial Surgery Clinics of North America·David A Fenton, Joseph F Piecuch
Aug 25, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Joseph F Piecuch
Jun 15, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Alonso Carrasco-LabraGordon Guyatt
Mar 9, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Romina Brignardello-PetersenPrakesh S Shah
Jan 3, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Alexander KatsnelsonThomas B Dodson
Nov 15, 2011·The Journal of Evidence-based Dental Practice·Poramate Pitak-Arnnop, Niels Christian Pausch
Aug 2, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Savannah GeleskoRaymond P White
Apr 26, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Omer Waleed Majid
Feb 15, 2011·The British Journal of Oral & Maxillofacial Surgery·Soudeh Chegini, Daljit K Dhariwal
Jan 11, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Hasan GaripKamil Göker
Nov 3, 2010·The British Journal of Oral & Maxillofacial Surgery·Omer Waleed Majid, Waseem Khalid Mahmood
Jul 2, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Anne E B DanElse M Pinholt
Feb 2, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Antonio BaroneUgo Covani
Nov 18, 2015·Oral and Maxillofacial Surgery·Janayna Gomes Paiva-OliveiraNelson Talatoci Oshiro-Filho
Jul 23, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Jennifer ChristensenSøren Schou
Aug 21, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Ibrahim MutluDaniel M Laskin
Mar 1, 2014·Physiotherapy Theory and Practice·Oliver RistowBettina Hohlweg-Majert
Jul 16, 2013·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Michael Wasson, O Ross Beirne
Aug 21, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Francisco Javier Herrera-BrionesManuel Vallecillo Capilla
May 4, 2016·Oral and Maxillofacial Surgery·Adebayo A Ibikunle, Wasiu L Adeyemo
Jul 12, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Erol CansizS Cemil Isler
Nov 12, 2016·Nigerian Medical Journal : Journal of the Nigeria Medical Association·Adebayo Aremu IbikunleAkinola Ladipo Ladeinde
Oct 23, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Eeva KormiJyrki Törnwall
Nov 29, 2016·The Journal of Craniofacial Surgery·Alípio Miguel Rocha-NetoBelmiro Cavalcanti do Egito Vasconcelos
Jan 13, 2018·Contemporary Clinical Dentistry·Adebayo Aremu Ibikunle, Wasiu Lanre Adeyemo

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