PMID: 46175Mar 7, 1975

Corticothalamic neurons and thalamocortical terminal fields: an investigation in rat using horseradish peroxidase and autoradiography

Brain Research
S Jacobson, J Q Trojanowski

Abstract

Subsequent to thalamic injections in rats of horseradish peroxidase (HRP) alone or HRP and [3H]leucine in combination, the cells of origin of the corticothalamic projections and the terminal fields of the thalamocortical projections were identified. HRP-labeled corticothalamic neurons were uniformly found in layers V and VI. They were medium to small in size and always pyramidal in shape with the larger neurons being found in layer V. On the other hand, 3 different patterns for the distribution of thalamocortical terminal fields were observed. The autoradiographic material indicated that in prefrontal cortex the bulk of thalamocortical fibers terminate in layer III while in motor cortex they terminate primarily in layer V. A third pattern was shared by temporal, occipital and parietal cortex where the bulk of thalamocortical fibers terminate preferentially in layer IV. The data derived from the rats which had received thalamic injections of HRP and [3H]leucine in combination indicated that the connections between cortex and thalamus are in general reciprocal. These results are discussed with regard to earlier studies using classical or more recently developed neuroanatomical methods.

References

Jul 12, 1974·Brain Research·P T Turner, A B Harris
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Citations

Jun 12, 1998·The Journal of Comparative Neurology·T D AumannM K Horne
Oct 24, 1975·Brain Research·J Q Trojanowski, S Jacobson
Jun 29, 1981·Brain Research·A J SeftonL J Cottee
Jan 1, 1983·Neuroscience and Biobehavioral Reviews·A Siegel, H Edinger
Jan 1, 1977·Neuroscience Letters·J C Hedreen
Sep 1, 1976·Brain Research Bulletin·R T Robertson
Nov 1, 1977·Brain Research Bulletin·P G Price, A W Fisher
Mar 1, 1988·Brain Research Bulletin·L D Aldes
Jul 17, 1999·Brain Research. Brain Research Reviews·T van GroenJ M Wyss
Apr 1, 1997·Progress in Neurobiology·M A Castro-Alamancos, B W Connors
Feb 6, 2009·Proceedings of the National Academy of Sciences of the United States of America·Adrian P KellsKrystof S Bankiewicz
Jul 1, 1991·Electroencephalography and Clinical Neurophysiology·S AbbesR Pumain
Aug 18, 2004·Annals of the New York Academy of Sciences·Erich D Jarvis
Jul 11, 2014·Frontiers in Neural Circuits·Carmen Varela
May 1, 1991·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K YamadaT Hayakawa
Oct 1, 1976·The Journal of Comparative Neurology·J Q Trojanowski, S Jacobson
Dec 8, 1985·The Journal of Comparative Neurology·J L Velayos, F Reinoso-Suárez

Related Concepts

Autoradiography
Axonal Transport
Insula of Reil
Structure of Broca's Area
Motor Cortex
Nerve Endings
Nervous System Structure
Neural Pathways
Occipital Lobe
Parietal Lobe

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