Cortisol Response to Stress in Adults with Attention Deficit Hyperactivity Disorder

The International Journal of Neuropsychopharmacology
Margarida Corominas-RosoJosep A Ramos-Quiroga

Abstract

Differences in the cortisol response have been reported between children exhibiting the inattentive and hyperactive/impulsive subtypes of attention deficit hyperactivity disorder. However, there is no such information about adults. The aim of the present study was to determine the possible differences between the combined and inattentive subtypes in the cortisol response to stress. Ninety-six adults with attention deficit hyperactivity disorder, 38 inattentive and 58 combined, without any medical or psychiatric comorbidities and 25 healthy controls were included. The Trier Social Stress Test was used to assess physiological stress responses. Clinical data and subjective stress levels, including the Perceived Stress Scale, were also recorded. No significant differences in the cortisol response to the Trier Social Stress Test were found between patients and controls. However, albeit there were no basal differences, lower cortisol levels at 15 (P=.015), 30 (P=.015), and 45 minutes (P=.045) were observed in the combined compared with the inattentive subtype after the stress induction; these differences disappeared 60 minutes after the stress. In contrast, the subjective stress responses showed significant differences between attent...Continue Reading

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Citations

Apr 17, 2016·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·J A Ramos-QuirogaM Casas
Jul 22, 2017·Stress and Health : Journal of the International Society for the Investigation of Stress·Alexander Lätsch
Nov 21, 2019·Nutrients·Stephanie Bull-Larsen, M Hasan Mohajeri
Sep 27, 2019·Frontiers in Integrative Neuroscience·Shelly J Lane, Stacey Reynolds
Sep 20, 2020·Translational Psychiatry·Cristine Marie Yde OhkiEdna Grünblatt
Jan 23, 2021·International Journal of Environmental Research and Public Health·Anna KrahelMonika Dmitrzak-Weglarz
Mar 10, 2021·Journal of Neural Transmission·Steffen BarraWolfgang Retz

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Software Mentioned

PASW Statistics

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