Corynebacterium glucuronolyticum causing genitourinary tract infection: Case report and review of the literature

IDCases
G GherardiV Savini

Abstract

Corynebacterium species are increasingly recognized as opportunistic pathogens. A growing number of taxonomic studies has yielded a description of numerous new Corynebacterium species, such as those related to the urogenital tract, with Corynebacterium glucuronolyticum found to be rarely involved in genitourinary tract infections, particularly in male individuals. In this report, we describe a urethritis case caused by C. glucuronolyticum in a 37-year-old, apparently healthy male, who complained mild pain in the lower abdomen, with several urinary symptoms. While urethral and semen specimens did not yield positive results for microbiological evaluation, cultures of urine samples revealed the monomicrobial growth on blood-containing media of tiny colonies after 24 h of incubation, clearly evident only after 48 h of incubation under CO2-enriched atmosphere. Colonies were identified as C. glucuronolyticum both by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) and 16S rRNA gene sequencing. Oral ciprofloxacin gradually led to clinical improvement and, finally, to a complete recovery, in accordance with microbiological findings. In spite of its infrequent detection, C. glucuronolyticum might be a potential uro...Continue Reading

References

Sep 7, 2007·Microbiology and Molecular Biology Reviews : MMBR·Marco VenturaDouwe van Sinderen
Sep 11, 2007·Journal of Comparative Pathology·G J Baird, M C Fontaine
Jun 20, 2008·Journal of Clinical Microbiology·Robert P RennieAnn Krilcich
Mar 26, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Fátima Galan-SanchezManuel Rodriguez-Iglesias
Jul 28, 2012·Journal of Clinical Microbiology·Kathryn Bernard
Sep 8, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·I Novo-VeleiroJ-L Pérez-Arellano
Feb 12, 2013·Folia Microbiologica·Vincenzo SaviniDomenico D'Antonio

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Citations

Jul 23, 2021·MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports·Kimberly A WorkowskiGail A Bolan

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