Coselected genes determine adaptive variation in herbivore resistance throughout the native range of Arabidopsis thaliana

Proceedings of the National Academy of Sciences of the United States of America
Benjamin BrachiJoy Bergelson

Abstract

The "mustard oil bomb" is a major defense mechanism in the Brassicaceae, which includes crops such as canola and the model plant Arabidopsis thaliana. These plants produce and store blends of amino acid-derived secondary metabolites called glucosinolates. Upon tissue rupture by natural enemies, the myrosinase enzyme hydrolyses glucosinolates, releasing defense molecules. Brassicaceae display extensive variation in the mixture of glucosinolates that they produce. To investigate the genetics underlying natural variation in glucosinolate profiles, we conducted a large genome-wide association study of 22 methionine-derived glucosinolates using A. thaliana accessions from across Europe. We found that 36% of among accession variation in overall glucosinolate profile was explained by genetic differentiation at only three known loci from the glucosinolate pathway. Glucosinolate-related SNPs were up to 490-fold enriched in the extreme tail of the genome-wide [Formula: see text] scan, indicating strong selection on loci controlling this pathway. Glucosinolate profiles displayed a striking longitudinal gradient with alkenyl and hydroxyalkenyl glucosinolates enriched in the West. We detected a significant contribution of glucosinolate loci...Continue Reading

References

Jun 13, 2001·Plant Physiology·D J KliebensteinT Mitchell-Olds
Feb 28, 2002·Phytochemistry·Michael ReicheltJonathan Gershenzon
Sep 25, 2003·Annual Review of Plant Biology·Sherry A Flint-GarciaEdward S Buckler
Sep 25, 2003·Proceedings of the National Academy of Sciences of the United States of America·Juergen KroymannThomas Mitchell-Olds
Oct 28, 2005·Genome Research·Rasmus NielsenCarlos Bustamante
Apr 21, 2006·PLoS Biology·Christopher ToomajianMagnus Nordborg
May 4, 2006·Annual Review of Plant Biology·Barbara Ann Halkier, Jonathan Gershenzon
Jun 27, 2008·Journal of Chemical Ecology·M Gabriela Bidart-Bouzat, Daniel J Kliebenstein
Sep 19, 2008·Plant Physiology·Jing LiBarbara Ann Halkier
Sep 25, 2008·Annual Review of Entomology·Richard J HopkinsJoop J A van Loon
Jul 25, 2009·PLoS Genetics·Nathaniel L ClarkWillie J Swanson
Mar 17, 2010·Current Opinion in Plant Biology·Meike BurowDaniel J Kliebenstein
Mar 23, 2010·Trends in Plant Science·Ida E SønderbyBarbara A Halkier
Nov 19, 2010·Nature Reviews. Genetics·Joy Bergelson, Fabrice Roux
Oct 8, 2011·Science·Angela M HancockJoy Bergelson
Oct 8, 2011·Science·A Fournier-LevelA M Wilczek
Oct 9, 2012·Science·Tobias ZüstLindsay A Turnbull
Nov 17, 2012·Nature Reviews. Genetics·Carrie F Olson-ManningThomas Mitchell-Olds
Apr 18, 2014·Nature Reviews. Genetics·Pak C Sham, Shaun M Purcell

❮ Previous
Next ❯

Citations

Mar 17, 2016·Proceedings of the National Academy of Sciences of the United States of America·Fabrice RouxFrançoise Budar
Oct 7, 2015·Frontiers in Plant Science·Lea M JensenMeike Burow
Feb 2, 2017·Annual Review of Plant Biology·Tobias Züst, Anurag A Agrawal
Jan 6, 2016·PLoS Biology·Meret HuberMatthias Erb
Oct 16, 2018·The New Phytologist·Amanda R De La TorreDavid B Neale
Nov 18, 2018·The Plant Journal : for Cell and Molecular Biology·Maricris L ZaidemMichael D Purugganan
Mar 23, 2018·G3 : Genes - Genomes - Genetics·Emma S T AllerMeike Burow
Apr 11, 2019·Molecular Biology and Evolution·Léa FrachonFabrice Roux
Mar 21, 2020·Molecular Biology and Evolution·Carrie F Olson-Manning
Jul 26, 2018·Frontiers in Plant Science·Léa FrachonFabrice Roux
Feb 21, 2019·Annual Review of Plant Biology·Matthias Erb, Philippe Reymond
Jan 25, 2019·Proceedings of the National Academy of Sciences of the United States of America·Bethany M MooreShin-Han Shiu
Jul 5, 2019·The Journal of Biological Chemistry·Süleyman GünalJonathan Wolf Mueller
Mar 1, 2017·Current Protocols in Plant Biology·Liana T BurghardtPeter Tiffin
Aug 5, 2018·Nature Ecology & Evolution·Sumitha NalluMarcus R Kronforst
Nov 5, 2019·Frontiers in Plant Science·Zheng WangXiao-Li Tan
Nov 27, 2018·Development, Growth & Differentiation·Masaru BambaTakashi Tsuchimatsu
May 16, 2020·Current Opinion in Plant Biology·Daniel J Kliebenstein
Dec 11, 2017·Trends in Plant Science·Matthias Erb
Nov 20, 2016·American Journal of Botany·Simon C Groen, Michael D Purugganan
Jun 3, 2021·International Journal of Molecular Sciences·Maria Hrmova, Syed Sarfraz Hussain
Jul 27, 2021·Frontiers in Plant Science·Harihar Jaishree SubrahmaniamFabrice Roux

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biodiversity Data

Biodiversity refers to the variety and variability of life on Earth. Biodiversity is typically a measure of variation at the genetic, species, and ecosystem level.Discover the latest research on biodiversity data here.