Cosmetic effectiveness of topically applied hydrolysed keratin peptides and lipids derived from wool

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
C BarbaL Coderch

Abstract

Skin moisturisation, elasticity, feel and appearance can all be improved through the topical application of protein hydrolysates. Recent studies suggest that supplementing intercellular lipids of the stratum corneum can enhance the functioning of the skin. In this study, a hydrolysed keratin peptide (molecular weight <1000 Da) was prepared from wool and tested on skin in two different formulations: an aqueous solution and an internal wool lipids (IWL) liposome suspension. In vivo long-term studies were performed to evaluate the water barrier function of the skin after topical application of different formulations. During the treatment period, hydration and elasticity were determined. A sorption-desorption test was also performed to assess the hygroscopic properties and water-holding capacity of the different treated skin sites. Significant differences were found between the control and treated sites, with the treated areas showing an increase in hydration and elasticity as a result of keratin peptide application. Measurements also indicated that the keratin formulations reinforce the skin barrier integrity, improving its water-holding capacity. A combination of the keratin peptide with the IWL showed beneficial effects, indicat...Continue Reading

References

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Citations

Feb 19, 2013·BMC Biotechnology·Ana Lúcia Vazquez VillaAlane Beatriz Vermelho
Jun 12, 2009·Journal of Liposome Research·R RamírezL Coderch
Jul 3, 2009·International Journal of Cosmetic Science·F Gorouhi, H I Maibach
Mar 5, 2011·Journal of Separation Science·Ana Valéria Colnaghi SimionatoMarina Franco Maggi Tavares
Apr 23, 2014·International Journal of Cosmetic Science·M V R VelascoA R Baby
Aug 14, 2015·Journal of Foot and Ankle Research·Farina HashmiSharon Lam
Apr 20, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Jiashen LiDangxia Zhou
Sep 7, 2016·Journal of Colloid and Interface Science·Fang PanJian R Lu
Mar 9, 2018·Royal Society Open Science·Shukun WangWei Zhao
Jun 28, 2019·Frontiers in Plant Science·Fabio AponeMaria Gabriella Colucci
Jan 5, 2021·Frontiers in Microbiology·Nonso E NnolimUchechukwu U Nwodo
May 11, 2021·3 Biotech·Chaitanya Reddy ChilakamarryBoya Narasaiah
Jul 3, 2021·Polymers·Simona Perța-CrișanFlorentina-Daniela Munteanu

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