CoSMoS unravels mysteries of transcription initiation.

Cell
Richard L Gourse, Robert Landick

Abstract

Using a fluorescence method called colocalization single-molecule spectroscopy (CoSMoS), Friedman and Gelles dissect the kinetics of transcription initiation at a bacterial promoter. Ultimately, CoSMoS could greatly aid the study of the effects of DNA sequence and transcription factors on both prokaryotic and eukaryotic promoters.

References

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Citations

Mar 7, 2013·Nature Communications·Antonio FilaretoRita C R Perlingeiro
Sep 21, 2012·Acta Crystallographica. Section D, Biological Crystallography·Seung Beom HongHyun Kyu Song
Jan 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·Masayoshi HondaMaria Spies
Aug 24, 2013·Chemical Society Reviews·Joshua D LarsonAaron A Hoskins
Jul 20, 2018·Biological Reviews of the Cambridge Philosophical Society·Yaolai WangFeng Liu
Aug 18, 2021·The Journal of Biological Chemistry·Chun-Ying Lee, Sua Myong

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