Cost analysis of nucleic acid amplification for diagnosing pulmonary tuberculosis, within the context of the Brazilian Unified Health Care System

Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Márcia PintoAnete Trajman

Abstract

We estimated the costs of a molecular test for Mycobacterium tuberculosis and resistance to rifampin (Xpert MTB/RIF) and of smear microscopy, within the Brazilian Sistema Único de Saúde (SUS, Unified Health Care System). In SUS laboratories in the cities of Rio de Janeiro and Manaus, we performed activity-based costing and micro-costing. The mean unit costs for Xpert MTB/RIF and smear microscopy were R$35.57 and R$14.16, respectively. The major cost drivers for Xpert MTB/RIF and smear microscopy were consumables/reagents and staff, respectively. These results might facilitate future cost-effectiveness studies and inform the decision-making process regarding the expansion of Xpert MTB/RIF use in Brazil.

References

Jun 14, 2012·PloS One·Gesine Meyer-RathSydney Rosen
Mar 28, 2013·The Lancet Infectious Diseases·Stephen D LawnAlimuddin Zumla
Sep 13, 2013·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·H W ChoiM Shah

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Citations

Mar 14, 2019·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Tatiane Maria da SilvaAdriana Dos Santos
Jan 7, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Neil E RensJason R Andrews
Feb 7, 2019·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Rogério Souza
Nov 22, 2017·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Massimo AmicosanteUNKNOWN TB Diagnostic Survey Working Group
May 24, 2018·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Marilda CaselaEliana Dias Matos
Feb 8, 2018·Respiratory Medicine·Denise Rossato SilvaGiovanni Battista Migliori

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Software Mentioned

Sigtap
GeneXpert
Xpert

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