Cost and Resource Use of Pemphigus and Pemphigoid Disorders Pre- and Post-Rituximab

Journal of Cutaneous Medicine and Surgery
Kara HeelanNicole Mittmann

Abstract

Rituximab (RTX) is increasingly used for the treatment of pemphigus and pemphigoid disorders. The high cost of RTX frequently limits its use and access. To determine the health system resources and costs associated with RTX treatment of pemphigus and pemphigoid. Health system resources and costs attributed to a convenience sample of 89 patients with either pemphigus or pemphigoid were identified, quantified, and valued 6 months prior to and following RTX initiation between May 2006 and August 2012. Overall cohort costs and costs per patient were calculated (2013 Can$). The overall cohort cost for 6 months pre-RTX was $3.8 million and for 6 months post-RTX was $2.6 million. The average cost per patient decreased from $42,231 to $29,423 (30.3% decrease). The main cost driver was intravenous immunoglobulin. Our findings suggest that RTX is effective in reducing health system resources and the costs associated with the treatment of pemphigus and pemphigoid.

References

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Citations

Jan 23, 2016·Journal of the American Academy of Dermatology·Amy HuangJacob Levitt
Jul 18, 2015·Journal of the American Academy of Dermatology·Romi Bloom, Kyle T Amber
Feb 18, 2017·The Australasian Journal of Dermatology·Aaron J RobinsonLaura Scardamaglia
Aug 9, 2018·The Journal of Dermatological Treatment·Jordan M KeeleyNaveed Sami
Jan 25, 2020·Expert Review of Pharmacoeconomics & Outcomes Research·V BrodszkyF Rencz
Sep 22, 2018·Drugs·Kyle T AmberMichael Hertl
Oct 14, 2020·Immunotherapy·Gérôme BohelayPhilippe Musette
Jul 11, 2021·Indian Journal of Dermatology, Venereology and Leprology·Anuradha BishnoiRahul Mahajan

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Methods Mentioned

BETA
biopsy

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