Cost-Benefit Analysis of Malaria Chemoprophylaxis and Early Diagnosis for Korean Soldiers in Malaria Risk Regions

Journal of Korean Medical Science
Hee Sung KimMinyoung Kim

Abstract

Chemoprophylaxis has been used to prevent malaria among soldiers and secondary transmission, as it effectively facilitates a decline in disease occurrence and secondary prevention. However, poor compliance and decreased risk of exposure to malaria necessitate that control strategies be reestablished. To predict the incidence of malaria according to a control strategy, we proposed a mathematical model for its transmission using epidemiological data from 2010 to 2012. The benefit component included in the analyses was the averted cost with each control strategy, and the cost components were the cost of implementing chemoprophylaxis and early diagnosis. The chemoprophylaxis regimen with hydroxychloroquine sulfate and primaquine was Intervention 1, the regimen with primaquine only was Intervention 2, and diagnosis with a rapid diagnostic test (RDT) kit within 5 days of fever was Intervention 3. The simulation indicated that the combined control program with chemoprophylaxis and early diagnosis would be the most effective strategy, whereas sole early diagnosis would be the least effective strategy. However, the cost-benefit ratio of chemoprophylaxis was less than Intervention 1, irrespective of the varying range of chemoprophylaxis ...Continue Reading

References

Jan 25, 2003·Parasitology International·Hirofumi IshikawaJudson Leafasia
May 1, 1953·The American Journal of Tropical Medicine and Hygiene·R F FRITZ, J M ANDREWS
Oct 15, 2005·Journal of Korean Medical Science·Joon-Sup YeomJae-Won Park
Aug 26, 2006·The American Journal of Tropical Medicine and Hygiene·Fabrizio TediosiMarcel Tanner
Jul 14, 2007·The Journal of Parasitology·F Ellis McKenzieWilliam E Collins
Aug 22, 2009·The Lancet Infectious Diseases·Ivo MuellerHernando A del Portillo
Nov 4, 2009·The Korean Journal of Parasitology·Jae-Won ParkJoon-Sup Yeom
Nov 7, 2009·Journal of the Royal Society, Interface·O DiekmannM G Roberts
Nov 5, 2011·Malaria Journal·Michael T WhiteAzra C Ghani
Nov 11, 2011·The Korean Journal of Parasitology·Desmond H FoleyHeung Chul Kim
Sep 21, 2013·Journal of Medical Microbiology·Joel C Mouatcho, J P Dean Goldring

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