Cost-Effectiveness Analysis of Breast Reconstruction Options in the Setting of Postmastectomy Radiotherapy Using the BREAST-Q

Plastic and Reconstructive Surgery
Shantanu N RazdanEvan Matros

Abstract

A consensus is lacking on a uniform reconstructive algorithm for patients with locally advanced breast cancer who require postmastectomy radiotherapy. Both delayed autologous and immediate prosthetic techniques have inherent advantages and complications. The study hypothesis is that implants are more cost effective than autologous reconstruction in the setting of postmastectomy radiotherapy because of immediate restoration of the breast mound. A cost-effectiveness analysis model using the payer perspective was created comparing delayed autologous and immediate prosthetic techniques against the do-nothing option of mastectomy without reconstruction. Costs were obtained from the 2010 Nationwide Inpatient Sample database. Effectiveness was determined using the BREAST-Q patient-reported outcome measure. A breast quality-adjusted life-year value was considered 1 year of perfect breast health-related quality of life. The incremental cost-effectiveness ratio was calculated for both treatments compared with the do-nothing option. BREAST-Q scores were obtained from patients who underwent immediate prosthetic reconstruction (n = 196), delayed autologous reconstruction (n = 76), and mastectomy alone (n = 71). The incremental cost-effectiv...Continue Reading

References

Nov 5, 1997·Plastic and Reconstructive Surgery·J K WilliamsG Mackay
Apr 29, 2004·Plastic and Reconstructive Surgery·Steven J KronowitzGeoffrey L Robb
Jul 2, 2009·Plastic and Reconstructive Surgery·Emily S HuAmy K Alderman
Aug 1, 2009·Plastic and Reconstructive Surgery·Andrea L PusicStefan J Cano
Aug 1, 2009·Plastic and Reconstructive Surgery·Steven J Kronowitz, Geoffrey L Robb
Jul 27, 2011·Plastic and Reconstructive Surgery·Maurizio B NavaGiuseppe Catanuto
Mar 14, 2013·The Laryngoscope·Luke Rudmik, Michael Drummond
Oct 30, 2013·Plastic and Reconstructive Surgery·Ritwik GroverEmily B Ridgway
Nov 10, 2013·Annals of Surgical Oncology·Colleen M McCarthyAndrea L Pusic
Aug 28, 2014·Plastic and Reconstructive Surgery·Claudia R AlbornozEvan Matros
Aug 28, 2014·Journal of the American College of Surgeons·Claudia R AlbornozEvan Matros
Aug 28, 2014·The New England Journal of Medicine·Peter J NeumannMilton C Weinstein
Aug 30, 2014·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Judith BerbersLiesbeth J Boersma
Dec 4, 2014·Annals of Surgical Oncology·Dunya M AtishaAmy P Abernethy
Jan 8, 2015·Annals of Surgical Oncology·Shailesh AgarwalAdeyiza O Momoh

❮ Previous
Next ❯

Citations

Aug 23, 2018·Cancer Control : Journal of the Moffitt Cancer Center·Johanna H YunAmber G Orman
Jan 24, 2019·Annals of Surgical Oncology·Alexander Y YoonAbhishek Chatterjee
Nov 26, 2019·Plastic and Reconstructive Surgery·Jonas A NelsonAndrea L Pusic
Nov 9, 2019·Journal of Plastic Surgery and Hand Surgery·Emma HanssonLars Sandman
Nov 30, 2018·Plastic and Reconstructive Surgery·Charalampos SiotosCarisa M Cooney
May 23, 2020·Plastic and Reconstructive Surgery. Global Open·Gabriel BouhadanaPeter G Davison
May 27, 2020·Plastic and Reconstructive Surgery·Andres F DovalAnthony Echo
Oct 8, 2020·Plastic and Reconstructive Surgery·Mauro BaronePaolo Persichetti
Dec 12, 2020·International Journal of Environmental Research and Public Health·Soo-Kyung BokSohyun Jin
Jan 12, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Korri S HershenhouseKetan M Patel
May 22, 2021·Plastic and Reconstructive Surgery·Jonas A NelsonEvan Matros
Jul 17, 2021·The Breast : Official Journal of the European Society of Mastology·Renée Ml MiseréRené Rwj van der Hulst

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.