Cost-effectiveness analysis of introducing universal childhood rotavirus vaccination in Bangladesh

Human Vaccines & Immunotherapeutics
Abdur Razzaque SarkerAlec Morton

Abstract

Diarrhea is one of the world's leading killers of children, and globally, rotavirus is the most common cause of severe diarrhea among under 5 children. In Bangladesh, rotavirus kills nearly 6,000 under 5 children in each year. To reduce the burden of childhood rotavirus diseases, universal rotavirus vaccination is recommended by World Health Organization. The objective of this study is to assess the cost-effectiveness of introducing universal childhood rotavirus vaccination with the newly developed ROTAVAC vaccine in national Expanded Programme of Immunization in Bangladesh. We developed a decision model to examine the potential impact of vaccination in Bangladesh and to examine the effect if the vaccination is applied in the nationwide immunization program schedule. Introduction of childhood universal rotavirus vaccination in Bangladesh scenario appears as highly cost-effective and would offer substantial future benefits for the young population if vaccinated today. The cost per DALY averted of introducing the rotavirus vaccine compared with status quo is approximately US$ 740.27 and US$ 728.67 per DALY averted from the health system and societal perspective respectively which is "very cost-effective" using GDP threshold level...Continue Reading

References

Oct 3, 1996·The New England Journal of Medicine·F R VelázquezG M Ruiz-Palacios
Nov 16, 2001·Microbes and Infection·O Lundgren, L Svensson
May 17, 2005·American Journal of Preventive Medicine·Matthew T McKennaJames S Marks
Oct 20, 2005·The Journal of Infectious Diseases·Thea K FischerJoseph S Bresee
Jan 6, 2006·The New England Journal of Medicine·Guillermo M Ruiz-PalaciosUNKNOWN Human Rotavirus Vaccine Study Group
Jan 6, 2006·The New England Journal of Medicine·Timo VesikariUNKNOWN Rotavirus Efficacy and Safety Trial (REST) Study Team
Aug 26, 2006·Vaccine·E T IsakbaevaJ S Bresee
Nov 7, 2007·The Pediatric Infectious Disease Journal·Go TanakaUmesh D Parashar
Jun 10, 2009·Health Policy·Marion HaasSophia Schlette
Oct 13, 2009·The Journal of Infectious Diseases·Elmira T FlemRichard D Rheingans
Oct 13, 2009·The Journal of Infectious Diseases·Deborah AtherlyRichard D Rheingans
Oct 13, 2009·The Journal of Infectious Diseases·Omayra OrtegaMark S Riddle
Oct 14, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Marc JeulandUNKNOWN DOMI Cholera Economics Study Group
Nov 26, 2009·Vaccine·Jacqueline E TateGagandeep Kang
Jan 29, 2010·The New England Journal of Medicine·Shabir A MadhiKathleen M Neuzil
Apr 2, 2010·International Journal of Epidemiology·Melinda K MunosRobert E Black
Apr 24, 2010·Vaccine·Maggie BrysonJessica Bryson
Apr 21, 2011·PharmacoEconomics·Mark Jit, Marc Brisson
Sep 29, 2011·Vaccine·Mark JitLiudmila Mosina
Oct 31, 2012·Bulletin of the World Health Organization·Shaun K MorrisUNKNOWN Million Death Study Collaborators
Jan 26, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Evan J AndersonGary A Noskin
Jun 19, 2013·Pediatrics·Margaret M CorteseMarietta Vázquez
Aug 21, 2013·Human Vaccines & Immunotherapeutics·E Anthony S NelsonDuncan Steele
May 20, 2014·Bulletin of the World Health Organization·Patrick LydonJean-Marie Okwo-Bele
Aug 6, 2014·Vaccine·Nita BhandariUNKNOWN India Rotavirus Vaccine Group
Aug 20, 2014·Proceedings of the National Academy of Sciences of the United States of America·Till BärnighausenJennifer Carroll O'Brien

❮ Previous
Next ❯

Citations

Jan 11, 2018·Global Health Research and Policy·Abdur Razzaque SarkerAlec Morton
Dec 28, 2018·Tropical Medicine and Infectious Disease·Abdur Razzaque SarkerAlec Morton
Jul 23, 2020·PharmacoEconomics·David D KimPeter J Neumann
Dec 5, 2020·Expert Review of Vaccines·Philippe BuchyGyneth Lourdes Bibera
Sep 16, 2021·Health Policy and Planning·Emily SchuellerRamanan Laxminarayan

❮ Previous
Next ❯

Software Mentioned

TRIVAC
Excel

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.