Cost-effectiveness analysis of resorbable biosynthetic mesh in contaminated ventral hernia repair.

Journal of Visceral Surgery
D Charleux-MullerC Lejeune

Abstract

The aim of this study was to compare, in terms of cost and serious complications, the use of biosynthetic resorbable parietal mesh with biologic mesh in patients undergoing contaminated ventral hernia repair (modified Ventral Hernia Working Group grade 3). Poly-4-hydroxy-butyrate (P4HB) biosynthetic mesh has rarely been the subject of comparative studies in the context of contamination. Data are required to confirm the effects of a transition from biological mesh to biosynthetic resorbable mesh. A cost-effectiveness analysis was conducted. It was based on a decision analysis model built with clinical and economic data issued from a before-after study that included 94 patients hospitalized for ventral hernia repair at the University Hospital of Strasbourg (France) from June 2011 to February 2018. The effectiveness endpoint was the number of patients presenting with a serious specific complication or a general complication at 6 months. Data for surgical hospitalization stays, home hospitalizations and ambulatory care costs were included. We found fewer serious complications with biosynthetic mesh: 21% versus 33% with biologic mesh. A cost savings of US $5146 was determined. Deterministic sensitivity analyses and a probabilistic a...Continue Reading

References

Aug 10, 2000·The New England Journal of Medicine·R W LuijendijkJ Jeekel
Apr 22, 2005·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Andrew Briggs
Aug 31, 2010·Journal of the American College of Surgeons·Charles E ButlerCarmen N Rios
Sep 10, 2011·Hernia : the Journal of Hernias and Abdominal Wall Surgery·B K PouloseM D Holzman
Sep 25, 2012·Journal of the American College of Surgeons·Arielle E KantersMichael J Rosen
Sep 27, 2012·American Journal of Surgery·Evan W BealeAndrew P Trussler
Apr 16, 2013·The Journal of Surgical Research·David P MartinJeffrey R Scott
May 27, 2014·Surgery·Gayan S De SilvaYuri W Novitsky
Jul 25, 2015·Journal of the American College of Surgeons·Julie L HolihanMike K Liang
Jun 12, 2016·Surgical Endoscopy·Margaret A PlymaleJ Scott Roth
Aug 17, 2016·Surgery·Ciara R HuntingtonVedra A Augenstein
Sep 6, 2018·Journal of Visceral Surgery·D Moszkowicz, J-L Bouillot
Sep 30, 2018·Journal of Visceral Surgery·C Law-KiP Ortega-Deballon
Oct 26, 2018·Journal of the American College of Surgeons·Steven SchneebergerBenjamin K Poulose
Jan 26, 2021·Hernia : the Journal of Hernias and Abdominal Wall Surgery·D Charleux-MullerB Romain

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