Cost-effectiveness and patient tolerance of low-attenuation oral contrast material: milk versus VoLumen

AJR. American Journal of Roentgenology
Chi Wan KooDavid H Frager

Abstract

The purpose of our study was to prospectively compare the cost, effectiveness, and patient tolerance of milk and VoLumen, a 0.1% barium suspension, in patients undergoing abdominal and pelvic CT with oral and i.v. contrast media. Two hundred fifteen consecutive outpatients were randomly assigned to receive either whole milk (n = 115) or VoLumen (n = 100). Results were independently reviewed by two radiologists who were blinded to the oral contrast agent used. Degree of bowel distention was qualitatively scored on a 4-point scale, and bowel wall visibility was graded qualitatively on a yes-or-no basis. A questionnaire regarding oral contrast tolerability was provided to each patient. Cost comparison of the two agents was performed. No statistically significant differences were seen between whole milk and VoLumen with respect to degree of bowel distention and mural visualization for all segments of bowel studied (p > 0.05 for both reviewers). Significantly more patients ranked milk as pleasant in taste compared with VoLumen (p < 0.0001). More patients preferred milk compared with VoLumen (p < 0.0001). Milk was better tolerated than VoLumen, with fewer abdominal side effects, including abdominal discomfort (p = 0.019), cramping (p...Continue Reading

Associated Clinical Trials

Oct 8, 2020·Nahla Mostafa Mahmoud Bashank

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Jun 11, 2010·Pediatric Radiology·Rutger A J NievelsteinAart J van der Molen
May 4, 2012·The British Journal of Radiology·R IlangovanS A Taylor
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Jul 30, 2016·Journal of Medical Imaging and Radiation Oncology·Jessica WongChris McKee

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