Cost-Effectiveness of a Specialized Oral Nutritional Supplementation for Malnourished Older Adult Patients in Spain

Nutrients
María D Ballesteros-PomarAlejandro Sanz-Paris

Abstract

Malnutrition has been related to prolonged hospital stays, and to increases in readmission and mortality rates. In the NOURISH (Nutrition effect On Unplanned Readmissions and Survival in Hospitalized patients) study, administering a high protein oral nutritional supplement (ONS) containing beta-hydroxy-beta-methylbutyrate (HP-HMB) to hospitalised older adult patients led to a significant improvement in survival compared with a placebo treatment. The aim of this study was to determine whether HP-HMB would be cost-effective in Spain. We performed a cost-effectiveness analysis from the perspective of the Spanish National Health System using time horizons of 90 days, 180 days, 1 year, 2 years, 5 years and lifetime. The difference in cost between patients treated with HP-HMB and placebo was €332.75. With the 90 days time horizon, the difference in life years gained (LYG) between both groups was 0.0096, resulting in an incremental cost-effectiveness ratio (ICER) of €34,700.62/LYG. With time horizons of 180 days, 1 year, 2 years, 5 years and lifetime, the respective ICERs were €13,711.68, €3377.96, €2253.32, €1127.34 and €563.84/LYG. This analysis suggests that administering HP-HMB to older adult patients admitted to Spanish hospitals...Continue Reading

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Citations

Sep 8, 2018·Internal and Emergency Medicine·Emanuele RinninellaMaria Cristina Mele
Jul 19, 2019·European Eating Disorders Review : the Journal of the Eating Disorders Association·Patricia Yárnoz-EsquírozGema Frühbeck
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Sep 1, 2019·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·D SeguyA Raynaud-Simon

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