Cost-Effectiveness of Caries Prevention in Practice: A Randomized Controlled Trial

Journal of Dental Research
Ciaran O'NeillM Tickle

Abstract

A 2-arm parallel-group randomized controlled trial measured the cost-effectiveness of caries prevention in caries-free children aged 2 to 3 y attending general practice. The setting was 22 dental practices in Northern Ireland. Participants were centrally randomized into intervention (22,600 ppm fluoride varnish, toothbrush, a 50-mL tube of 1,450 ppm fluoride toothpaste, and standardized prevention advice) and control (advice only), both provided at 6-monthly intervals during a 3-y follow-up. The primary outcome measure was conversion from caries-free to caries-active states assessed by calibrated and blinded examiners; secondary outcome measures included decayed, missing, or filled teeth surfaces (dmfs); pain; and extraction. Cumulative costs were related to each of the trial's outcomes in a series of incremental cost effectiveness ratios (ICERs). Sensitivity analyses examined the impact of using dentist's time as measured by observation rather than that reported by the dentist. The costs of applying topical fluoride were also estimated assuming the work was undertaken by dental nurses or hygienists rather than dentists. A total of 1,248 children (624 randomized to each group) were recruited, and 1,096 (549 in the intervention ...Continue Reading

References

Apr 15, 2000·Journal of Dental Research·M L MattilaP Paunio
Aug 4, 2005·Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community·Peter McNeeJane Davies
May 24, 2007·Community Dentistry and Oral Epidemiology·A I IsmailN B Pitts
Sep 4, 2013·Acta Odontologica Scandinavica·I MejàreS Twetman
Apr 5, 2017·Journal of Dental Research·M TickleH V Worthington
Jun 3, 2017·Journal of Dental Research·E Hall-ScullinT Walsh

❮ Previous
Next ❯

Citations

Jul 7, 2017·Community Dentistry and Oral Epidemiology·Falk SchwendickeLyndie Foster Page
Dec 8, 2017·Expert Review of Pharmacoeconomics & Outcomes Research·Nathalia Miranda LadewigDaniela Prócida Raggio
Feb 21, 2019·Community Dentistry and Oral Epidemiology·Raul PalacioChristopher Robert Vernazza
Apr 21, 2020·Journal of Public Health Dentistry·Rodrigo MariñoCarlos Zaror
Jul 28, 2019·International Journal of Environmental Research and Public Health·Nadine FraihatOrsolya Varga
Dec 23, 2017·Community Dentistry and Oral Epidemiology·Lucy O'MalleyMartin Tickle
Dec 29, 2020·Acta Odontologica Scandinavica·Thomas DavidsonSofia Tranæus
Jun 21, 2019·Caries Research·Fernanda Santos de Oliveira de SousaBranca Heloisa de Oliveira
Sep 11, 2020·Caries Research·Alex D McMahonLorna M D Macpherson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.