PMID: 2504443Aug 1, 1989Paper

Cost-effectiveness of CT scanning compared with mediastinoscopy in the preoperative staging of lung cancer

Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes
R J Eddy

Abstract

In lung cancer, evaluation of the mediastinum is a critical factor in the determination of surgical resectability. Mediastinoscopy with nodal biopsy has been the preferred method of assessing the mediastinum. An alternate approach is to first perform computed tomography (CT) and then decide on the need for further tests. The present study is a cost-effectiveness analysis of these two diagnostic strategies. A decision tree was constructed incorporating the two approaches. Costs were determined in a rigorous manner by calculating a fully allocated unit price for all relevant hospital services. These costs include both direct costs and an appropriate share of support and overhead expenses. The frequency of complications with the tests, the need for further tests, and the expected outcomes for the patients were derived from published data. Hospital charts were reviewed to determine the amount of services used by patients who had actually experienced the outcomes or complications of interest. The comparative costs of the two strategies were then determined by multiplying the fully allocated unit costs by the amount of services that a cohort of patients could be expected to use following one or the other pathway. The strategy employi...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Medical Decision Making : an International Journal of the Society for Medical Decision Making
D J MalenkaJ R Beck
The Journal of Thoracic and Cardiovascular Surgery
J B RubinsD E Niewoehner
© 2022 Meta ULC. All rights reserved