Cost effectiveness of drug-eluting stents in acute myocardial infarction patients in Germany: results from administrative data using a propensity score-matching approach

Applied Health Economics and Health Policy
Michael BäumlerReinhard Busse

Abstract

The high number of patients with acute myocardial infarction (AMI) has facilitated greater research, resulting in the development of innovative medical devices. So far, results from economic evaluations that compared drug-eluting stents (DES) and bare-metal stents (BMS) have not shown clear evidence that one intervention is more cost effective than the other. The aim of this study was to measure the cost effectiveness of DES compared with BMS in routine care. We used administrative data from a large German sickness fund to compare the costs and effectiveness of DES and BMS in patients with AMI. Patients with hospital admission after AMI in 2004 and 2005 were followed up for 1 year after hospital discharge. The cost of treatment and survival after 365 days were compared for patients treated with DES and BMS. We adjusted for covariates defined according to the Ontario Acute Myocardial Infarction Mortality Prediction Rules using propensity score matching. After matching, we calculated incremental cost-effectiveness ratios (ICERs) by (i) using sample means based on bootstrapping procedures and (ii) estimating generalized linear mixed models for costs and survival. After propensity score matching, the sample included 719 patients tr...Continue Reading

References

Sep 1, 1996·Progress in Cardiovascular Diseases·Y OzakiP W Serruys
Feb 22, 2001·The American Journal of Medicine·P A Heidenreich, M McClellan
Mar 27, 2001·Journal of the American College of Cardiology·J V TuK M McDonald
Jul 17, 2001·American Journal of Rhinology·W T Anselmo-Lima, V J Lund
Sep 18, 2001·Health Affairs·D M Cutler, M McClellan
Oct 13, 2006·Health Economics·Edward EvansEun-Hwan Oh
Nov 2, 2006·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Onur Baser
Oct 5, 2007·The New England Journal of Medicine·Jack V TuRon Goeree
Nov 21, 2007·Journal of Health Economics·David M Cutler
Dec 7, 2007·International Journal of Cardiology·Birga MaierUNKNOWN Berlin Myocardial Infarction Registry
May 24, 2008·Journal of the American College of Cardiology·Peter W GroeneveldFeifei Yang
Jun 3, 2008·American Heart Journal·Peter W GroeneveldFeifei Yang
Oct 24, 2008·Biometrics·Dennis D BoosYujun Wu
Apr 1, 2009·International Journal of Technology Assessment in Health Care·Ron GoereeJack V Tu
Jun 6, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Matthias BischofAlain Nordmann
Aug 26, 2010·Journal of Interventional Cardiology·Cornelia HenschkeReinhard Busse
Jan 8, 2011·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Annemieke De Ridder, Diana De Graeve

❮ Previous
Next ❯

Citations

Apr 25, 2012·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·J Schreyögg, T Stargardt
Feb 7, 2014·International Journal of Technology Assessment in Health Care·Michael BäumlerDaniel Böhringer
Apr 11, 2018·BMC Health Services Research·Fabia Mareike Gansen
Feb 16, 2020·International Journal of Environmental Research and Public Health·Elizabeth Parody-RúaIgnacio Aznar-Lou

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy
Harald Walach
Journal of Public Health Management and Practice : JPHMP
Robert J LaLonde
Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Mattias NeytChris De Laet
© 2021 Meta ULC. All rights reserved