Cost-effectiveness of fine-needle-aspiration cytology of thyroid nodules with intranodular vascular pattern using two different needle types.

Endocrine Pathology
Carlo CappelliE Agabiti Rosei

Abstract

To compare the cytological findings of hypoechoic thyroid nodules with intranodular vascular pattern (pattern II) obtained by two different needles (Neolus 25 gauge, Chemil, Wenzhou, China vs Yale Spinal 25 gauge, Becton Dickinson, Madrid, Spain) in euthyroid patients and to evaluate their cost-effectiveness. From January 2001 to December 2003, 480 euthyroid patients with a hypoechoic thyroid nodule pattern II were referred for US-FNAC. The nodules were alternatively evaluated by Neolus or by Yale Spinal with the stylet (YS+) or without the stylet (YS-), in order to evaluate if the cytological results could be due to the presence of the stylet or to the different length of the two needles. For each nodule two passes were performed and the material was obtained by capillary action. Material was smeared on slides, fixed, and stained by Papanicolaou techniques. Cytological specimens were evaluated in blind by the same experienced cytopathologist. Inadequate cytological specimens because of blood contamination were present in 30 (18.7%) samples by Neolus needle and in 22 (13.8%) by YS- compared to only 5 (3.1%) by YS+. In 6 (20%) cases of the 30 repeated US-FNAC by Neolus and in 4 (18%) of the 22 US-FNAC by YS-, material remained i...Continue Reading

Citations

Aug 17, 2006·Thyroid : Official Journal of the American Thyroid Association·Carlo Cappelli, Enrico Agabiti Rosei
Feb 26, 2008·Journal of Endocrinological Investigation·C CappelliE Agabiti Rosei
Mar 8, 2008·Clinical Radiology·C CappelliE Agabiti Rosei
Jul 28, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Won-Jin MoonYoung Kee Shong
Jan 22, 2008·Cytopathology : Official Journal of the British Society for Clinical Cytology·C CappelliM Castellano
Apr 26, 2006·BMC Cancer·René ScheidenCatherine Capesius
Dec 3, 2008·Nature Clinical Practice. Endocrinology & Metabolism·Carlo Cappelli
Jun 24, 2010·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Alptekin GursoySemra Ayturk
Apr 18, 2009·Southern Medical Journal·Carlo CappelliMaurizio Castellano

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