Cost-effectiveness of interventions to improve hand hygiene in healthcare workers in middle-income hospital settings: a model-based analysis

The Journal of Hospital Infection
N LuangasanatipB S Cooper

Abstract

Multi-modal interventions are effective in increasing hand hygiene (HH) compliance among healthcare workers, but it is not known whether such interventions are cost-effective outside high-income countries. To evaluate the cost-effectiveness of multi-modal hospital interventions to improve HH compliance in a middle-income country. Using a conservative approach, a model was developed to determine whether reductions in meticillin-resistant Staphylococcus aureus bloodstream infections (MRSA-BSIs) alone would make HH interventions cost-effective in intensive care units (ICUs). Transmission dynamic and decision analytic models were combined to determine the expected impact of HH interventions on MRSA-BSI incidence and evaluate their cost-effectiveness. A series of sensitivity analyses and hypothetical scenarios making different assumptions about transmissibility were explored to generalize the findings. Interventions increasing HH compliance from a 10% baseline to ≥20% are likely to be cost-effective solely through reduced MRSA-BSI. Increasing compliance from 10% to 40% was estimated to cost US$2515 per 10,000 bed-days with 3.8 quality-adjusted life-years (QALYs) gained in a paediatric ICU (PICU) and US$1743 per 10,000 bed-days with ...Continue Reading

References

Jun 1, 1991·The Journal of Hospital Infection·S Ponce-de-Leon
Apr 6, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Didier PittetStephan Harbarth
Oct 12, 2004·The Journal of Hospital Infection·E S McBrydeD L S McElwain
Feb 28, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Nicholas GravesMichael Whitby
Jun 3, 2008·The Medical Journal of Australia·M Lindsay GraysonUNKNOWN Hand Hygiene Study Group and Hand Hygiene Statewide Roll-out Group, Victorian Quality Council
Jul 16, 2008·Journal of Clinical Epidemiology·Jan BeyersmannMartin Schumacher
Aug 22, 2008·International Journal of Nursing Practice·Wilawan PicheansathianPrakin Suchaxaya
Dec 17, 2009·American Journal of Infection Control·Anucha ApisarnthanarakVictoria J Fraser
Dec 19, 2009·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Benedetta AllegranziUNKNOWN World Health Organization "Point G" Project Management Committee
Jan 22, 2010·Critical Care : the Official Journal of the Critical Care Forum·Brian H CuthbertsonLuke Vale
Feb 25, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nicholas GravesBen Cooper
Mar 16, 2011·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Adrian G BarnettMartin Wolkewitz
Mar 30, 2011·Critical Care : the Official Journal of the Critical Care Forum·Emilio SacanellaAlfonso López-Soto
Apr 21, 2011·PharmacoEconomics·Mark Jit, Marc Brisson
Mar 27, 2013·BMJ : British Medical Journal·Don HusereauUNKNOWN CHEERS Task Force
Jul 3, 2013·BMC Infectious Diseases·Esther van KleefWilliam J Edmunds
Oct 5, 2013·Critical Care : the Official Journal of the Critical Care Forum·Nantasit LuangasanatipBen S Cooper
Jul 16, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Adrian G BarnettNicholas Graves
Aug 6, 2014·The Journal of Hospital Infection·K PageN Graves
Sep 10, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Andrew J StewardsonUNKNOWN TIMBER Study Group
Jul 30, 2015·BMJ : British Medical Journal·Nantasit LuangasanatipBen S Cooper
Nov 22, 2017·Wellcome Open Research·Esther van KleefBen S Cooper

❮ Previous
Next ❯

Software Mentioned

etm
deSolve
R

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.