Cost Effectiveness of Preventive Treatment for Tuberculosis in Special High-Risk Populations

PharmacoEconomics
Roland DielAlbert Nienhaus

Abstract

In view of the goal of eliminating tuberculosis (TB) by 2050, economic evaluations of interventions against the development of TB are increasingly requested. Little research has been published on the incremental cost effectiveness of preventative therapy (PT) in groups at high risk for progression from latent TB infection (LTBI) with Mycobacterium TB (MTB) to active disease. A systematic review of studies with a primary focus on model-driving inputs and methodological differences was conducted. A search of MEDLINE, the Cochrane Library and EMBASE to July 2014 was undertaken, and reference lists of eligible articles and relevant reviews were examined. A total of 876 citations were retrieved, with a total of 24 studies being eligible for inclusion, addressing six high-risk groups other than contact persons. Results varied considerably between studies and countries, and also over time. Although the selected studies generally demonstrated cost effectiveness for PT in HIV-infected subjects and healthcare workers (HCWs), the outcome of these analyses can be questioned in light of recent epidemiologic data. For immigrants from high TB-burden countries, patients with end-stage renal disease, and the immunosuppressed, now defined as fur...Continue Reading

References

Aug 12, 1974·JAMA : the Journal of the American Medical Association·R P PradhanR P Eisinger
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·K Schwartzman, D Menzies
May 23, 2001·Pediatrics·H FroehlichUNKNOWN Pediatric Tuberculosis Study Group of Kaiser Permanente, Northern California
May 10, 2002·The European Respiratory Journal·J F BroekmansUNKNOWN World Health Organization, International Union Against Tuberculosis and Lung Disease, and Royal Netherlands Tuberculosis Ass
May 6, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R S WallisD O Beenhouwer
Jan 8, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Shelley R Salpeter, Edwin E Salpeter
Jun 21, 2006·BMC Public Health·Travis C PorcoSarah E Royce
Jul 20, 2007·Bulletin of the World Health Organization·Mario C Raviglione
Sep 8, 2007·BMC Public Health·Catherine R StevensonNigel Unwin
Sep 5, 2008·PharmacoEconomics·Christopher McCabeAnthony J Culyer
Jan 28, 2009·Archives of Internal Medicine·Marie A de PerioMark H Eckman
Jan 22, 2010·The Cochrane Database of Systematic Reviews·Christopher AkoloJimmy Volmink
Nov 27, 2010·Journal of Epidemiology and Community Health·F YoungM J Goldacre
Mar 30, 2011·PLoS Medicine·Alice ZwerlingMadhukar Pai
May 13, 2011·American Journal of Respiratory and Critical Care Medicine·Benjamin P LinasC Robert Horsburgh
Oct 4, 2011·BMC Health Services Research·Albert NienhausRoland Diel
Dec 27, 2011·Drug Discovery Today·Hanif EsmailRobert J Wilkinson
Jan 13, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Meghan A BakerMegan B Murray
Apr 13, 2012·The European Respiratory Journal·Dragos BumbaceaMartina Sester
Jul 13, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Benjamin L LaskinMark H Eckman
Oct 9, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lauren A LambertMaryam B Haddad
Nov 13, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·M Teresa del CampoJaime Esteban
Dec 15, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Akiko Kowada
Feb 12, 2013·The European Respiratory Journal·Roland DielUNKNOWN European Forum for TB Innovation
Aug 21, 2013·Digestive Diseases and Sciences·Mike van der HaveMartijn G H van Oijen
Jan 23, 2014·Annals of the American Thoracic Society·Manish JoshiGail L Woods
Jan 24, 2014·The New England Journal of Medicine·Gavin J ChurchyardUNKNOWN Thibela TB Study Team
Aug 12, 2014·Annals of Internal Medicine·Helen R StaggIbrahim Abubakar
Oct 25, 2014·Annals of the American Thoracic Society·Neil W Schluger, Joseph Burzynski

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Citations

Feb 3, 2016·Current Opinion in Infectious Diseases·Meredith L Turetz, Kevin C Ma
Apr 4, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Kayvan BozorgmehrChristian Stock
Jan 13, 2018·Tuberculosis Research and Treatment·Kwame Owusu-EduseiRoque Miramontes

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