Cost-Effectiveness of Screening for Intermediate Age-Related Macular Degeneration during Diabetic Retinopathy Screening

Ophthalmology
Christina K W ChanDavid S H Wong

Abstract

To determine whether screening for age-related macular degeneration (AMD) during a diabetic retinopathy (DR) screening program would be cost effective in Hong Kong. We compared and evaluated the impacts of screening, grading, and vitamin treatment for intermediate AMD compared with no screening using a Markov model. It was based on the natural history of AMD in a cohort with a mean age of 62 years, followed up until 100 years of age or death. Subjects attending a DR screening program were recruited. A cost-effectiveness analysis was undertaken from a public provider perspective. It included grading for AMD using the photographs obtained for DR screening and treatment with vitamin therapy for those with intermediate AMD. The measures of effectiveness were obtained largely from a local study, but the transition probabilities and utility values were from overseas data. Costs were all from local sources. The main assumptions and estimates were tested in sensitivity analyses. The outcome was cost per quality-adjusted life year (QALY) gained. Both costs and benefits were discounted at 3%. All costs are reported in United States dollars ($). The cost per QALY gained through screening for AMD and vitamin treatment for appropriate cases...Continue Reading

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Feb 13, 2018·Diabetes, Obesity & Metabolism·Carlos K H WongCindy L K Lam
Jan 7, 2020·Current Opinion in Ophthalmology·Nicholas Y Q TanChelvin C A Sng
Sep 18, 2016·Applied Health Economics and Health Policy·Thomas ButtGary Rubin
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Jul 31, 2021·Journal of the American Heart Association·Chao-Chien ChangChien-An Sun

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