Cost-effectiveness of strategies to increase cervical screening uptake at first invitation (STRATEGIC)

Journal of Medical Screening
Apostolos TsiachristasA Gray

Abstract

Objective To assess the cost-effectiveness of strategies to increase cervical cancer screening uptake at first invitation (STRATEGIC trial). Methods We performed an economic analysis alongside the STRATEGIC trial, comparing each of seven novel interventions for improving cervical screening uptake with control general practices in Greater Manchester and Grampian (United Kingdom). A template was developed to measure the intervention costs. Trial estimates of screening uptake were combined with data from the literature to estimate healthcare costs of each intervention. The added lifetime costs and quality adjusted life years (QALYs) of attending cervical screening were estimated by a systematic literature review, with relevant results pooled and weighted by study quality. Trial results and estimated lifetime costs and benefits of screening were then combined in a decision analytic model, giving an incremental cost per QALY gained for each intervention. Uncertainty was addressed in probabilistic and univariate sensitivity analyses. Results Intervention costs per screening round per woman attending varied from about £1.20 (2014 UK) for the nurse navigator intervention to £62 for the unrequested HPV self-sampler kit. The meta-analysi...Continue Reading

References

Jul 21, 2004·Lancet·Julian PetoFiona E Matthews
Sep 14, 2004·Health Technology Assessment : HTA·Z PhilipsJ Glanville
Jul 28, 2010·Journal of Medical Screening·L LancuckiJ Patnick
Mar 15, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J FerlayF Bray
Mar 27, 2013·BMJ : British Medical Journal·Don HusereauUNKNOWN CHEERS Task Force
Sep 17, 2016·Health Technology Assessment : HTA·Henry C KitchenerChris Roberts

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Citations

Oct 30, 2019·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Helen E CampbellOliver Rivero-Arias
Dec 19, 2019·European Journal of Public Health·João Firmino-MachadoNuno Lunet
Jul 8, 2020·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Stephen RocksApostolos Tsiachristas
Mar 9, 2021·Expert Review of Pharmacoeconomics & Outcomes Research·Samuel N FrempongGurdeep S Sagoo
Jul 17, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Rebecca A DennisonSimon J Griffin

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