Cost-Effectiveness of Supplemental Donor Milk Versus Formula for Very Low Birth Weight Infants

Pediatrics
Susan TrangGTA DoMINO Feeding Group

Abstract

To determine the cost-effectiveness of supplemental donor human milk (DHM) versus preterm formula (PTF) for very low birth weight (VLBW, <1500 g) infants from a societal perspective to 18 months' corrected age. This prospective cost-effectiveness analysis of 363 VLBW infants was conducted for a randomized control trial. Infants recruited from October 2010 to December 2012 were fed DHM or PTF whenever mother's milk was unavailable. Formal health care costs for initial hospitalization and readmissions were obtained from standardized cost-accounting systems and physician fees. Informal and nonhealth care sector costs (eg, caregiver transportation, labor market earnings) were calculated from parent reports. Mean infant birth weight was 996 (SD, 272) grams. Incidence of necrotizing enterocolitis (NEC) differed between groups (all stages 3.9% DHM, 11.0% PTF; P = .01). Costs to 18 months did not differ with a mean (95% confidence interval) of 217 624 (197 697-237 551) and 217 245 (196 494-237 995) 2015 Canadian dollars in the DHM and PTF groups. Postdischarge costs were lower in the DHM (46 440 [40 648-52 233]) than PTF group (55 102 [48 269-61 934]) (P = .04), driven by parent lost wages. DHM cost an additional $5328 per case of aver...Continue Reading

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Citations

Aug 25, 2020·Journal of Human Lactation : Official Journal of International Lactation Consultant Association·Kimberly MansenKiersten Israel-Ballard
Aug 20, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Atoosa F CraigheadDmitry Dukhovny
Nov 16, 2018·Frontiers in Pediatrics·Shelley BrandstetterKiersten Israel-Ballard
Jan 7, 2021·Maternal & Child Nutrition·Natalie ShenkerUNKNOWN Virtual Collaborative Network of Milk Banks and Associations
Sep 27, 2020·The Journal of Pediatrics·Juan D RiosUNKNOWN Canadian Neonatal Network Investigators
Feb 3, 2021·Maternal & Child Nutrition·Mandana ZanganehHema Mistry
Feb 15, 2021·Seminars in Perinatology·Brian C KingJohn A F Zupancic
Jan 5, 2021·Current Opinion in Pediatrics·Souvik Mitra, Douglas McMillan
Mar 2, 2021·The Journal of Pediatrics·Katie M StrobelUNKNOWN University of California Fetal Consortium
Jul 13, 2021·Journal of Midwifery & Women's Health·Yeon Bai, Jennifer Kuscin
Jul 25, 2021·International Journal of Environmental Research and Public Health·Cornelia WiechersAxel R Franz
Aug 21, 2021·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Jennifer HanfordJohn Pardalos
Aug 17, 2020·Value in Health Regional Issues·Aleksandra WesolowskaDominik Golicki
Sep 26, 2021·Journal of Perinatology : Official Journal of the California Perinatal Association·Ashwini LakshmananCynthia L Gong
Apr 12, 2019·Neonatology·Verena Walsh, William McGuire
Nov 10, 2021·American Journal of Perinatology·Nilesh SeshadriJoseph M Collaco

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