Cost-efficient FPGA implementation of basal ganglia and their Parkinsonian analysis

Neural Networks : the Official Journal of the International Neural Network Society
Shuangming YangHuiyan Li

Abstract

The basal ganglia (BG) comprise multiple subcortical nuclei, which are responsible for cognition and other functions. Developing a brain-machine interface (BMI) demands a suitable solution for the real-time implementation of a portable BG. In this study, we used a digital hardware implementation of a BG network containing 256 modified Izhikevich neurons and 2048 synapses to reliably reproduce the biological characteristics of BG on a single field programmable gate array (FPGA) core. We also highlighted the role of Parkinsonian analysis by considering neural dynamics in the design of the hardware-based architecture. Thus, we developed a multi-precision architecture based on a precise analysis using the FPGA-based platform with fixed-point arithmetic. The proposed embedding BG network can be applied to intelligent agents and neurorobotics, as well as in BMI projects with clinical applications. Although we only characterized the BG network with Izhikevich models, the proposed approach can also be extended to more complex neuron models and other types of functional networks.

References

Dec 19, 1991·Nature·M Mahowald, R Douglas
Nov 14, 2003·The New England Journal of Medicine·Paul KrackPierre Pollak
Dec 4, 2003·Parkinsonism & Related Disorders·J D PutzkeR J Uitti
Apr 29, 2004·Journal of Computational Neuroscience·Jonathan E Rubin, David Terman
Mar 8, 2005·Neuron·Helen S MaybergSidney H Kennedy
May 11, 2005·Scientific American·Kwabena Boahen
Mar 3, 2006·Journal of Neural Engineering·Randall K Weinstein, Robert H Lee
Sep 1, 2006·The New England Journal of Medicine·Günther DeuschlUNKNOWN German Parkinson Study Group, Neurostimulation Section
Oct 4, 2006·Neuron·Thomas Wichmann, Mahlon R Delong
Dec 15, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mark D HumphriesKevin N Gurney
Dec 28, 2006·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Terrence S T MakChi-Sang Poon
Feb 7, 2007·IEEE Transactions on Neural Networks·R Jacob VogelsteinGert Cauwenberghs
Apr 18, 2007·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Randall K WeinsteinRobert H Lee
Feb 5, 2008·IEEE Transactions on Neural Networks·E M Izhikevich
Jun 17, 2008·Journal of Computational Neuroscience·Marco PiriniLorenzo Chiari
Jun 13, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Daqing Guo, Chunguang Li
Apr 7, 2010·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Steven J Schiff
Jul 13, 2011·Frontiers in Neuroscience·Giacomo IndiveriKwabena Boahen
Aug 3, 2011·Frontiers in Neuroanatomy·José A Obeso, José L Lanciego
Oct 4, 2011·Journal of Physiology, Paris·Horacio Rostro-GonzalezCesar Torres-Huitzil
Mar 19, 2013·Frontiers in Neural Circuits·Paolo BonifaziMichela Chiappalone
Jul 13, 2013·Frontiers in Computational Neuroscience·Corey M Thibeault, Narayan Srinivasa
Sep 4, 2013·Nanotechnology·Giacomo IndiveriThemistoklis Prodromakis
Sep 24, 2013·Frontiers in Neuroscience·Jennifer Hasler, Bo Marr
May 9, 2014·IEEE Transactions on Neural Networks and Learning Systems·Takashi Matsubara, Hiroyuki Torikai
May 17, 2014·Annals of Biomedical Engineering·Frédéric D BroccardGert Cauwenberghs

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Citations

Sep 15, 2018·Neural Computation·Rongxin BaoRuixin Ma
May 31, 2018·Biomedizinische Technik. Biomedical Engineering·Behrouz Alizadeh SavarehMahyar Ghafoori
Jun 26, 2020·Frontiers in Neuroscience·Frank Klefenz, Tamas Harczos
Dec 23, 2016·Journal of Integrative Neuroscience·Charlotte HéricéAndré Garenne
Oct 28, 2019·Frontiers in Neuroscience·Farnaz FaramarziBernabé Linares-Barranco
Mar 9, 2021·Frontiers in Neuroscience·Shuangming YangBernabe Linares-Barranco
Mar 16, 2021·Frontiers in Neuroscience·Pablo StoliarMarcelo J Rozenberg

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