Cost of illness of non-alcoholic liver cirrhosis in Japan: A time trend analysis and future projections

Hepatology Research : the Official Journal of the Japan Society of Hepatology
Takefumi KitazawaTomonori Hasegawa

Abstract

Liver cirrhosis is a preneoplastic condition to hepatocellular carcinoma that is an important worldwide public health concern, and its economic burden has been estimated in some countries. The objective of this study was to estimate and predict the cost of illness (COI) associated with non-alcoholic liver cirrhosis in Japan. Using a COI method on available data from government statistics, we estimated the economic burden in 3-year intervals from 1996 to 2014. We then predicted the COI in 3-year intervals from 2017 to 2029 using fixed and variable model estimations. With fixed model estimation, only the estimated future population was used as a variable. Variable model estimation considered the time trends of health-related indicators throughout the past 18 years. The estimated COI of non-alcoholic liver cirrhosis was ¥208.1bn in 2014. The COI of non-alcoholic liver cirrhosis had a downward trend from 1996 to 2014. The predicted future COI of non-alcoholic liver cirrhosis was ¥144.3-210.5bn, ¥106.0-213.8bn, ¥88.6-213.4bn, ¥76.7-215.5bn, and ¥66.4-214.3bn in 2017, 2020, 2023, 2026, and 2029, respectively. The results of this study suggest that the COI of non-alcoholic liver cirrhosis in Japan has steadily decreased and will conti...Continue Reading

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Citations

May 26, 2018·Environmental Health and Preventive Medicine·Toshiharu GochiTomonori Hasegawa
Dec 7, 2020·Health Economics Review·Yinghui WuTomonori Hasegawa

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