Cost of treating peripheral neuropathic pain with pregabalin or gabapentin at therapeutic doses in routine practice

Journal of Comparative Effectiveness Research
A Sicras-MainarR Navarro-Artieda

Abstract

To analyze the cost of peripheral neuropathic pain (PNP) treatment with pregabalin or gabapentin at therapeutic doses in routine clinical practice. Analysis of a retrospective, observational study of electronic medical records of patients treated for PNP with therapeutic doses of pregabalin or gabapentin, with 2 years' follow-up, considering PNP type, comorbidities, concomitant analgesia and resource use. The weighted total average cost/patient was lower for pregabalin than gabapentin (€2464 [2197-2730] vs €3142 [2670-3614]; p = 0.014) due to significantly lower both healthcare and non-healthcare costs. This is explained by a significantly lower use of concomitant analgesia, fewer primary care visits and fewer days of sick leave. At therapeutic doses, pregabalin was found to have lower healthcare and non-healthcare costs than gabapentin in routine practice.

References

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Citations

Apr 30, 2020·BMJ : British Medical Journal·Stephanie MathiesonSam Eldabe
Apr 23, 2020·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Manuel E Machado-DuqueNatalia Castaño

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