Cost-utility analyses in diabetes: a systematic review and implications from real-world evidence

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Yue ZhongP J Neumann

Abstract

To systematically review the cost-effectiveness of diabetes interventions, identify high-value diabetes services, and estimate potential gains from increasing their utilization. The study consisted of two steps. First, we reviewed cost-utility analyses (CUAs) related to diabetes published through the end of 2012, using the Tufts Medical Center Cost-Effectiveness Analysis Registry (www.cearegistry.org). We used logistic regression to examine factors independently associated with favorable cost-effective ratios. Second, we used the Humedica electronic medical records to estimate potential savings and health benefits gained by shifting patients currently receiving low-value services to high-value alternatives. We identified 196 diabetes CUAs, of which 55% examined pharmaceuticals. Most (70%) diabetes CUAs focused on treatment rather than prevention. Most used a health care payer perspective and were industry-sponsored. Of the 497 published cost-utility ratios, 82% examined an intervention recommended by diabetes guidelines. Approximately 73% of the interventions were cost-saving or below $50,000 per quality-adjusted life-year. Logistic regression analysis showed that higher-quality CUAs, CUAs conducted from the US perspective, sur...Continue Reading

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Citations

Jul 6, 2015·Medicina clínica·Carles Zafon
Apr 25, 2016·Annals of Global Health·Jeffrey I Mechanick, Derek Leroith
Oct 27, 2017·Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences·Khosro KeshavarzShekoufeh Nikfar
Jul 19, 2017·Circulation·Anushka Patel, Laurent Billot
Apr 16, 2019·Critical Care Medicine·M Elizabeth WilcoxChaim M Bell
Sep 20, 2017·Community Dentistry and Oral Epidemiology·Ruvini M HettiarachchiPaul A Scuffham
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Oct 10, 2019·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·Yotsapon ThewjitcharoenThep Himathongkam

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