Cost-utility analysis of a medication review with follow-up service for older adults with polypharmacy in community pharmacies in Spain: the conSIGUE program

PharmacoEconomics
Francisco Jódar-SánchezShalom I Benrimoj

Abstract

The concept of pharmaceutical care is operationalized through pharmaceutical professional services, which are patient-oriented to optimize their pharmacotherapy and to improve clinical outcomes. The objective of this study was to estimate the incremental cost-effectiveness ratio (ICER) of a medication review with follow-up (MRF) service for older adults with polypharmacy in Spanish community pharmacies against the alternative of having their medication dispensed normally. The study was designed as a cluster randomized controlled trial, and was carried out over a time horizon of 6 months. The target population was older adults with polypharmacy, defined as individuals taking five or more medicines per day. The study was conducted in 178 community pharmacies in Spain. Cost-utility analysis adopted a health service perspective. Costs were in euros at 2014 prices and the effectiveness of the intervention was estimated as quality-adjusted life-years (QALYs). In order to analyze the uncertainty of ICER results, we performed a non-parametric bootstrapping with 5000 replications. A total of 1403 older adults, aged between 65 and 94 years, were enrolled in the study: 688 in the intervention group (IG) and 715 in the control group (CG). ...Continue Reading

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Citations

Dec 30, 2015·Journal of Evaluation in Clinical Practice·Joanna C MoullinShalom I Benrimoj
Nov 10, 2016·Expert Review of Pharmacoeconomics & Outcomes Research·A Malet-LarreaE Goyenechea
Sep 3, 2016·The Annals of Pharmacotherapy·Todd GammieZaheer-Ud-Din Babar
Apr 24, 2017·International Journal of Clinical Pharmacy·Aranzazu NoainShalom I Benrimoj
Feb 18, 2018·International Journal of Clinical Pharmacy·Marian Z M HurmuzJeannette G van Manen
Sep 4, 2018·The Cochrane Database of Systematic Reviews·Audrey RankinCarmel Hughes
Jun 5, 2015·International Journal of Clinical Pharmacy·Carla Castrillon OcampoMiguel Angel Gastelurrutia
Sep 13, 2019·Applied Health Economics and Health Policy·Jenny ClelandJulie Ratcliffe
Jan 28, 2020·Journal of Clinical Pharmacy and Therapeutics·Takayuki MabuchiMitsutaka Takada
Oct 12, 2017·BMC Geriatrics·Nashwa MasnoonGillian E Caughey
Mar 20, 2019·Canadian Pharmacists Journal : CPJ = Revue Des Pharmaciens Du Canada : RPC·Sherilyn K D HouleKelly A Grindrod
Dec 4, 2016·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Amaia Malet-LarreaShalom I Benrimoj
May 15, 2018·The Annals of Pharmacotherapy·Vanessa Alves-ConceiçãoDivaldo Pereira de Lyra-Jr
Aug 21, 2020·Journal of General Internal Medicine·Hanna E BloomfieldTimothy J Wilt
Mar 27, 2020·Pharmacy : Journal of Pharmacy, Education and Practice·Mira El-SouriCharlotte Rossing
Oct 1, 2020·International Journal of Clinical Pharmacy·Nuria García-Agua SolerFrancisco Jódar-Sánchez
Nov 20, 2016·International Journal of Clinical Pharmacy·Elza Aparecida Machado DominguesMiguel Ángel Calleja-Hernández
Nov 29, 2016·British Journal of Clinical Pharmacology·Jean-Baptiste BeuscartAnne Spinewine
Jan 20, 2021·Research in Social & Administrative Pharmacy : RSAP·Beatriz Pérez-EscamillaVictoria Garcia-Cardenas
Feb 6, 2021·Journal of Comparative Effectiveness Research·Antonio Ahumada-CanaleVictoria Garcia-Cardenas
Jan 6, 2021·Journal of Pharmaceutical Policy and Practice·Nadia Farhanah SyafhanJames C McElnay
Nov 15, 2018·Research in Social & Administrative Pharmacy : RSAP·Sanne VerdoornMarcel L Bouvy
Jul 10, 2021·Journal of the American Pharmacists Association : JAPhA·Betul OkuyanHilal Ozcebe
Aug 18, 2021·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Basmah AlbabtainEjaz Cheema

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