Cost-utility and cost-effectiveness of physical exercise during adjuvant chemotherapy

The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care
Hanna van WaartNeil K Aaronson

Abstract

A home-based, low-intensity physical activity program (Onco-Move) and a supervised, moderate-to-high intensity, combined resistance and aerobic exercise program (OnTrack) have proven to be effective in maintaining physical fitness and reducing fatigue among breast cancer patients undergoing adjuvant chemotherapy. This study evaluated the cost-utility and cost-effectiveness of Onco-Move and OnTrack. A total of 230 patients were randomized to Onco-Move, OnTrack, or usual care (UC). Health outcomes included quality-adjusted life years (QALYs), general and physical fatigue, and physical fitness measured at baseline, end of chemotherapy, and 6-month follow-up. Societal costs included professional and informal health care, work absenteeism, and unpaid productivity costs. Cost data were based on 3-monthly questionnaires, supplemented by medication data obtained from pharmacies. Onco-Move is not likely to be cost-effective due to the relatively high willingness-to-pay necessary to reach reasonable probabilities of cost-effectiveness (QALY, general and physical fatigue). Incremental cost-effectiveness ratios for OnTrack compared to UC were €26,916/QALY, €788/1-point decrease in general fatigue and €1402/1-point decrease in physical fati...Continue Reading

References

Jan 1, 1990·Journal of Clinical Epidemiology·S S Coughlin
Apr 1, 1995·Journal of Psychosomatic Research·E M SmetsJ C De Haes
Jan 1, 1994·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C A Uyl-de GrootG J Bonsel
May 8, 1995·Journal of Health Economics·M A KoopmanschapL van Roijen
Dec 13, 2000·Statistics in Medicine·J A Barber, S G Thompson
Nov 6, 2003·Medicine and Science in Sports and Exercise·Kerry S Courneya
May 6, 2004·Health Economics·Elisabeth FenwickAndrew Briggs
Nov 2, 2005·Breast Cancer Research and Treatment·Louisa G GordonBeth Newman
Mar 1, 2006·British Journal of Sports Medicine·H P van der PloegW van Mechelen
Jul 11, 2007·Statistical Methods in Medical Research·Stef van Buuren
May 27, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Amanda PurcellTerry Haines
Jul 1, 2009·BMJ : British Medical Journal·Jonathan A C SterneJames R Carpenter
Jun 22, 2010·Cancer·Florence K TangkaEric A Finkelstein
Dec 15, 2010·Social Science & Medicine·Wei ZhangAslam H Anis
Jan 13, 2011·Statistics in Medicine·Ian R WhiteAngela M Wood
Nov 28, 2012·Journal of Pain and Symptom Management·Louise JonesAdrian Tookman
Mar 19, 2014·Medicine and Science in Sports and Exercise·Kerry S CourneyaJohn R Mackey

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Citations

Mar 12, 2019·Worldviews on Evidence-based Nursing·Jingchun ZengLiming Lu
Sep 17, 2019·Medicine and Science in Sports and Exercise·Jonna K VAN VulpenLaurien M Buffart
Jul 31, 2019·American Journal of Physical Medicine & Rehabilitation·Duc HaJames D Murphy
Apr 19, 2019·Breast Cancer Research and Treatment·Kamran Ahmad KhanJulie Bruce
Oct 17, 2019·CA: a Cancer Journal for Clinicians·Kathryn H SchmitzCharles E Matthews
Nov 16, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lionel PerrierBéatrice Fervers
Aug 10, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Hanna van WaartNeil K Aaronson
Oct 25, 2020·Scandinavian Journal of Medicine & Science in Sports·Ana Myriam Lavín-PérezAlfonso Jiménez
Dec 18, 2020·Cancer·Kathryn H SchmitzDiane C Farley
Jan 2, 2021·JNCI Cancer Spectrum·Alice AvanciniSara Pilotto
Nov 25, 2020·International Journal of Environmental Research and Public Health·Louisa G GordonSandra C Hayes
Feb 25, 2021·Journal of Cancer Survivorship : Research and Practice·Barbara E Gubler-GutSabine Rohrmann
May 9, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Amy M DennettCasey L Peiris
Jul 9, 2021·Cancer Reports·Melanie PotiaumpaiKathryn H Schmitz

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