Costs and effects in therapy for acute coronary syndromes: the case of abciximab in high-risk patients undergoing percutaneous transluminal coronary angioplasty in the EPIC study. Evaluation of 7E3 for the Prevention of Ischemic Complications

American Heart Journal
B A van HoutM L Simoons

Abstract

Cost-effectiveness analyses are routinely performed to determine whether the additional cost of a novel therapy is balanced by additional effectiveness. The definitions of costs and effects involve a variety of assumptions, both in general economic terms and with regard to the specific medical setting under consideration. Similarly, differing criteria for acceptability of cost-effectiveness estimates can be used to generate different conclusions regarding cost-effectiveness. The issues and problems inherent in economic evaluation are discussed by an analysis of findings with the platelet glycoprotein IIb/IIIa inhibitor abciximab in the EPIC (Evaluation of 7E3 for the Prevention of Ischemic Complications) study in high-risk patients undergoing percutaneous transluminal coronary angioplasty.

References

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Sep 2, 1993·The New England Journal of Medicine·UNKNOWN GUSTO investigators
Mar 11, 1993·The New England Journal of Medicine·F ZijlstraH Suryapranata
Jun 12, 1997·The New England Journal of Medicine·UNKNOWN EPILOG Investigators
Aug 1, 1997·Social Science & Medicine·E Elsinga, F F Rutten

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