Could nutritional and functional status serve as prognostic factors for COVID-19 in the elderly?

Medical Hypotheses
Irene LidorikiDimitrios Schizas

Abstract

Geriatric patients seem to be the most vulnerable group in COVID-19. These patients are usually characterized by impaired mobilization and malnutrition. In addition, obesity has been correlated with increased mortality rates after COVID-19 infection, highlighting the role of nutrition in prognosis of COVID-19 as well. In the past, several indices of nutritional status (GNRI) and functional status (ECOG performance status, Barthel Index, Handgrip Strength) have demonstrated a prognostic ability for hospitalized patients with influenza-like respiratory infections from coronavirus, metapneumovirus, parainfluenza and rhinovirus. Our hypothesis suggests that the previously mentioned nutritional and functional status indices, combined with the pneumonia severity index (CRB-65), could be useful in prognosis of morbidity and mortality of the elderly after the novel COVID-19 infection. Our hypothesis, is the first in the literature, which suggests a prognostic association between nutritional status of patients and COVID-19 infection, offering a quick and low-cost prognostic tool for COVID-19 in the elderly.

Citations

Oct 10, 2020·Aging Clinical and Experimental Research·Guerino RecinellaMarco Zoli
Jan 30, 2021·Current Medical Research and Opinion·Jessica Abadía OteroJosé Pablo Miramontes González
Dec 29, 2020·Frontiers in Cellular and Infection Microbiology·Dan-Cristian VodnarGheorghe-Adrian Martău
Jan 1, 2021·International Journal of General Medicine·Rosaria Del GiornoLuca Gabutti
Apr 4, 2021·Nutrients·Fiorenzo MoscatelliAntonietta Messina
Apr 10, 2021·Archives of Gerontology and Geriatrics·H D W T Damayanthi, K I P Prabani
Jun 27, 2021·Journal of the American Medical Directors Association·Marcel BallinPeter Nordström
Sep 30, 2021·The Journal of International Medical Research·Hui LiuHaiyan Yin
Dec 7, 2021·Inquiry : a Journal of Medical Care Organization, Provision and Financing·Irudaya Rajan SebastianYamuna Devi

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