Couple's Narratives of Communion and Isolation Following Abnormal Prenatal Microarray Testing Results

Qualitative Health Research
Allison Werner-LinBarbara A Bernhardt

Abstract

In 2% to 3% of cases, prenatal microarray testing detects deletions and duplications in a fetus' genome that are undetected by conventional cytogenetics. Many of these changes are associated with variable or uncertain symptomatology. Little is known about how couples experience uncertain results. This study analyzed 24 interviews with members of 12 heterosexual U.S. couples who received pathogenic or uncertain microarray prenatal testing results. Researchers used narrative analysis to examine couples' understanding and incorporation of findings into decision making regarding pregnancy termination. Couples felt unprepared for these findings and frustrated because scant information was available to aid interpretation. Women sought information and made decisions, and men marginalized their distress to support their wives. A shift in voice from first to second person indicated attempts to normalize emotional responses by making the process "common" to all couples. Families pursuing highly sensitive prenatal testing may need expert guidance to support decision making.

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Citations

May 22, 2016·Journal of Genetic Counseling·Allison Werner-LinBarbara A Bernhardt
Jul 19, 2016·American Journal of Obstetrics and Gynecology·UNKNOWN Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.orgJeffrey A Kuller
Mar 28, 2018·Qualitative Health Research·Mabel L S LieUNKNOWN MERIDIAN Collaborative Group
Jul 24, 2018·Prenatal Diagnosis·Karen WouWendy K Chung
Sep 6, 2018·Qualitative Health Research·Ruth M FarrellMarissa B Coleridge
Jun 5, 2019·Prenatal Diagnosis·Yael Hashiloni-DolevAviad Raz
Dec 29, 2018·Journal of Psychosocial Oncology·Jennifer L YoungAllison Werner-Lin
Apr 19, 2020·Maternal and Child Health Journal·Jennifer MarshallRussell S Kirby
Sep 3, 2020·Revista latino-americana de enfermagem·Celmira Laza-VásquezJuan Pablo Cano-Rivillas
Mar 28, 2018·Journal of Patient Experience·Patricia K AgatisaRuth M Farrell
Mar 20, 2019·Journal of Genetic Counseling·Casey E BrewCatherine Wicklund
Oct 2, 2019·Cold Spring Harbor Perspectives in Medicine·Blair Stevens
Jul 15, 2020·Gaceta sanitaria·Celmira Laza-VásquezErica Briones-Vozmediano

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