PMID: 11927682Apr 3, 2002Paper

Coupling between the ribs and the lung in dogs

The Journal of Physiology
A De Troyer, T A Wilson

Abstract

In contrast to the conventional theory, the external and internal intercostal muscles show marked rostrocaudal gradients in their actions on the lung. We hypothesized that these gradients are the result of a non-uniform coupling between the ribs and the lung. Rib displacements (X(r)) and the changes in airway opening pressure (P(a,o)) were thus measured in anaesthetized, pancuronium-treated, supine dogs while loads were applied in the cranial direction to individual pairs of odd-numbered ribs and in the caudal direction to individual pairs of even-numbered ribs. During cranial loading, X(r) induced by a given load increased gradually with increasing rib number. The decrease in P(a,o) also increased from the third to the fifth rib pair but then decreased markedly to the eleventh pair. A similar pattern was observed during caudal loading, although X(r) and DeltaP(a,o) were smaller. These results were then combined to calculate the net X(r) and the net DeltaP(a,o) that a hypothetical intercostal muscle lying parallel to the longitudinal body axis would produce in different interspaces. The net X(r) was cranial in all interspaces. However, whereas the net DeltaP(a,o) was negative in the cranial interspaces, it was positive in the c...Continue Reading

References

Jun 1, 1991·Journal of Applied Physiology·V NinaneM Estenne
Mar 1, 1985·The Journal of Clinical Investigation·A De TroyerW A Zin
Sep 1, 1982·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J Mead, S H Loring
Apr 1, 1983·Science·A De TroyerW A Zin
Aug 1, 1982·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·A De Troyer, S Kelly
Jun 22, 1999·The Journal of Physiology·A De TroyerT A Wilson

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Citations

Dec 25, 2003·The Journal of Physiology·André De Troyer, Dimitri Leduc
Sep 27, 2012·Acta Physiologica·D Negrini, A Moriondo
Jan 21, 2015·Respiratory Physiology & Neurobiology·Theodore A Wilson
Nov 16, 2004·Journal of Applied Physiology·André De Troyer
Mar 25, 2005·Physiological Reviews·André De TroyerTheodore A Wilson
May 17, 2014·Journal of Applied Physiology·A Navarrete-Opazo, G S Mitchell
Feb 14, 2015·Journal of Applied Physiology·André De Troyer, Theodore A Wilson
Feb 24, 2007·Journal of Applied Physiology·André De Troyer, Dimitri Leduc
Jun 20, 2006·Journal of Applied Physiology·André De Troyer, Dimitri Leduc
Jan 13, 2004·Journal of Applied Physiology·Theodore A Wilson, Andre De Troyer
Dec 3, 2011·Journal of Applied Physiology·André De Troyer
Apr 19, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Andrea MoriondoDaniela Negrini

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