Coupling of efferent neuromodulatory neurons to rhythmical leg motor activity in the locust

Journal of Neurophysiology
S BaudouxO T Morris

Abstract

The spike activity of neuromodulatory dorsal unpaired median (DUM) neurons was analyzed during a pilocarpine-induced motor pattern in the locust. Paired intracellular recordings were made from these octopaminergic neurons during rhythmic activity in hindleg motor neurons evoked by applying pilocarpine to an isolated metathoracic ganglion. This motor pattern is characterized by two alternating phases: a levator phase, during which levator, flexor, and common inhibitor motor neurons spike, and a depressor phase, during which depressor and extensor motor neurons spike. Three different subpopulations of efferent DUM neurons could be distinguished during this rhythmical motor pattern according to their characteristic spike output. DUM 1 neurons, which in the intact animal do not innervate muscles involved in leg movements, showed no change apart from a general increase in spike frequency. DUM 3 and DUM 3,4 neurons produced the most variable activity but received frequent and sometimes pronounced hyperpolarizations that were often common to both recorded neurons. DUM 5 and DUM 3,4,5 neurons innervate muscles of the hindleg and showed rhythmical excitation leading to bursts of spikes during rhythmic activity of the motor neurons, whic...Continue Reading

References

Jun 1, 1991·Journal of Neurobiology·M G GorczycaC F Wu
Jun 1, 1990·Trends in Neurosciences·H J ChielI Kupfermann
Jul 22, 1987·The Journal of Comparative Neurology·W Kutsch, H Schneider
Jul 1, 1986·Journal of Neurobiology·S N Zill
Mar 1, 1982·The Journal of Physiology·P D Evans, M V Siegler
Oct 31, 1980·Science·F Delcomyn
Jul 1, 1995·Journal of Neurophysiology·M Burrows, H J Pflüger
Aug 7, 1995·The Journal of Comparative Neurology·H R CampbellM V Siegler
Mar 1, 1995·Comparative Biochemistry and Physiology. Part A, Physiology·P A Stevenson, U Spörhase-Eichmann
May 1, 1993·Journal of Neurophysiology·S Ryckebusch, G Laurent
Feb 1, 1996·Trends in Neurosciences·P S Katz, W N Frost
Nov 1, 1996·Journal of Neurophysiology·R M Johnston, R B Levine

❮ Previous
Next ❯

Citations

Mar 13, 1999·The Journal of Comparative Neurology·C DuchH J Pflüger
May 17, 2007·Cell and Tissue Research·Natalia L Kononenko, Hans-Joachim Pflüger
Aug 16, 2011·Physiology·Hans-Joachim Pflüger, Carsten Duch
Apr 5, 2018·Frontiers in Systems Neuroscience·Bettina StockerHans-Joachim Pflüger
Aug 25, 2018·PloS One·Jens GoldammerJoachim Schmidt
Mar 5, 2020·Developmental Neurobiology·Charalampos MantziarisAnsgar Büschges
May 26, 2012·The Journal of Comparative Neurology·Mareike SelchoAndreas S Thum
Jan 15, 2000·Journal of Neurophysiology·V BrezinaK R Weiss
Nov 26, 2008·The Journal of Comparative Neurology·Natalia L KononenkoHans-Joachim Pflüger
Dec 23, 1999·Current Opinion in Neurobiology·H J Pflüger
Oct 13, 2007·Journal of Insect Physiology·Tim MentelHans-Joachim Pflüger
Nov 21, 2007·Journal of Insect Physiology·Laurence H FieldHans-Joachim Pflüger
Aug 4, 2011·Journal of Insect Physiology·Hans-Joachim PflügerMargaret J Currie

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.