Course of serum amyloid A (SAA) plasma concentrations in horses undergoing surgery for injuries penetrating synovial structures, an observational clinical study

BMC Veterinary Research
Eva HaltmayerTheresia F Licka

Abstract

Injuries penetrating synovial structures are common in equine practice and often result in septic synovitis. Significantly increased plasma levels of serum amyloid A (SAA) have been found in various infectious conditions in horses including wounds and septic arthritis. Plasma SAA levels were found to decrease rapidly once the infectious stimulus was eliminated. The purpose of the current study was to investigate the usefulness of serial measurements of plasma SAA as a monitoring tool for the response to treatment of horses presented with injuries penetrating synovial structures. In the current study plasma SAA concentrations were measured every 48 hours (h) during the course of treatment. A total of 19 horses with a wound penetrating a synovial structure were included in the current study. Horses in Group 1 (n = 12) (injuries older than 24 h) only needed one surgical intervention. Patients in this group had significantly lower median plasma SAA levels (P = 0.001) between 48 h (median 776 mg/L) and 96 h (median 202 mg/L) after surgery. A significant decrease (P = 0.004) in plasma SAA levels was also observed between 96 h after surgery (median 270 mg/L) and 6 days (d) after surgery (median 3 mg/L). Four horses (Group 2) required ...Continue Reading

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Citations

Dec 20, 2018·Equine Veterinary Journal·O D Witkowska-PiłaszewiczA Cywińska
Dec 21, 2019·BMC Veterinary Research·Stine JacobsenLise Nikolic Nielsen
Feb 24, 2020·Theriogenology·Igor F CanissoFabio S Lima
Feb 3, 2020·The Veterinary Clinics of North America. Equine Practice·Alicia Long, Rose Nolen-Walston

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BETA
lavage
lavages
sedation

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MedCalc

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