PMID: 2510676Sep 1, 1989Paper

Course of the radionuclide left ventricular ejection fraction at rest and during exercise in surgically treated asymptomatic chronic aortic insufficiency

Archives des maladies du coeur et des vaisseaux
A TissotJ E Besson

Abstract

In order to preserve left ventricular (LV) function, aortic valve replacement may be contemplated in asymptomatic patients with aortic regurgitation when LV dilatation and dysfunction are not too advanced. Our study involved 10 asymptomatic patients with severe, isolated and pure aortic regurgitation. Before, and 6 months after the operation, the LV ejection fraction (LVEF) was measured at rest and during exercise on an ergometric bicycle by radionuclide angiography (multigated technique). Mean preoperative values were: age 52 +/- 14 years; cardiothoracic ratio 0.55 +/- 0.04; end-diastolic LV diameter 69 +/- 9 mm; end systolic LV diameter 47 +/- 7 mm; LV fibre shortening fraction 0.31 +/- 0.03; LVEF 0.55 +/- 0.10 at rest and 0.41 +/- 0.13 at exercise. After surgery, the cardiothoracic ratio value (0.51 +/- 0.03) and the LVEF value at rest (0.60 +/- 0.07) were not significantly different from the corresponding preoperative values, but the LVEF value during exercise was significantly increased (0.58 +/- 0.11, p less than 0.001). Among the 9 patients who before surgery showed a fall in LVEF at exercise, after surgery 5 had a rise (group B) and 4 had a fall (group A) in LVEF at exercise. Before surgery, group A patients had greater...Continue Reading

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